OBJECTIVES: Serum amylase can be elevated in various pathological conditions, but its primary application is as a biochemical test for the diagnosis of acute pancreatitis. Acute gastroenteritis has not been widely recognized as a cause for hyperamylasemia and pancreatitis. METHODS: We describe a case of acute pancreatitis after rotavirus gastroenteritis occurring in a previously healthy child. RESULTS: Rotavirus infection was demonstrated by detection of virus particles in stool culture and pancreatitis by raised serum amylase and lipase levels. No abnormalities were noticed during clinical follow-up. CONCLUSIONS: Further investigation to understand the role of rotavirus as a cause of pancreatitis in children may be helpful.
OBJECTIVES: Serum amylase can be elevated in various pathological conditions, but its primary application is as a biochemical test for the diagnosis of acute pancreatitis. Acute gastroenteritis has not been widely recognized as a cause for hyperamylasemia and pancreatitis. METHODS: We describe a case of acute pancreatitis after rotavirus gastroenteritis occurring in a previously healthy child. RESULTS:Rotavirus infection was demonstrated by detection of virus particles in stool culture and pancreatitis by raised serum amylase and lipase levels. No abnormalities were noticed during clinical follow-up. CONCLUSIONS: Further investigation to understand the role of rotavirus as a cause of pancreatitis in children may be helpful.
Authors: Margo C Honeyman; David Laine; Yifan Zhan; Sarah Londrigan; Carl Kirkwood; Leonard C Harrison Journal: PLoS One Date: 2014-09-02 Impact factor: 3.240