Literature DB >> 2069385

Effect of abnormal levels of serum components on antibiotic activity.

B J Plotkin1, M Wright, A Lima, L Gruenberg.   

Abstract

Antibiotic activity in serum from a model for type II diabetes was similar to that in normal sera or media containing cholesterol but lacking glucose, insulin, or both. The ratio of effects of broth plus obese-rat serum to effects of broth plus lean-rat serum supplemented with cholesterol approached or equaled 1.

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Year:  1991        PMID： 2069385      PMCID： PMC245096          DOI： 10.1128/AAC.35.4.767

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  17 in total

1.  Very low density lipoprotein. Metabolism of phospholipids, cholesterol, and apolipoprotein C in the isolated perfused rat heart.

Authors:  T Chajek; S Eisenberg
Journal:  J Clin Invest       Date:  1978-06       Impact factor: 14.808

2.  Effects of diabetes mellitus on cholesterol metabolism in man.

Authors:  L J Bennion; S M Grundy
Journal:  N Engl J Med       Date:  1977-06-16       Impact factor: 91.245

3.  Genetic obesity in rats. I. The effects of food restriction on body composition and hypothalamic function.

Authors:  G A Bray; D A York; R S Swerloff
Journal:  Metabolism       Date:  1973-03       Impact factor: 8.694

4.  Laboratory tests of antifungal drugs.

Authors:  R J Holt
Journal:  J Clin Pathol       Date:  1975-10       Impact factor: 3.411

5.  Serum dilution test for bactericidal activity. I. Selection of a physiologic diluent.

Authors:  C W Stratton; L B Reller
Journal:  J Infect Dis       Date:  1977-08       Impact factor: 5.226

6.  Serum dilution test for bactericidal activity. II. Standardization and correlation with antimicrobial assays and susceptibility tests.

Authors:  L B Reller; C W Stratton
Journal:  J Infect Dis       Date:  1977-08       Impact factor: 5.226

Review 7.  Influence of obesity on drug disposition.

Authors:  R A Blouin; J H Kolpek; H J Mann
Journal:  Clin Pharm       Date:  1987-09

Review 8.  The Zucker-fatty rat: a review.

Authors:  G A Bray
Journal:  Fed Proc       Date:  1977-02

9.  Amikacin pharmacokinetics in morbidly obese patients.

Authors:  L A Bauer; R A Blouin; W O Griffen; K E Record; R M Bell
Journal:  Am J Hosp Pharm       Date:  1980-04

10.  Lipoproteins and plasma cholesterol esterification in normal and diabetic subjects.

Authors:  M B Mattock; J H Fuller; P S Maude; H Keen
Journal:  Atherosclerosis       Date:  1979-12       Impact factor: 5.162
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