Literature DB >> 20693605

Xenohormetic, hormetic and cytostatic selective forces driving longevity at the ecosystemic level.

Alexander A Goldberg1, Pavlo Kyryakov, Simon D Bourque, Vladimir I Titorenko.   

Abstract

We recently found that lithocholic acid (LCA), a bile acid, extends yeast longevity. Unlike mammals, yeast do not synthesize bile acids. We therefore propose that bile acids released into the environment by mammals may act as interspecies chemical signals providing longevity benefits to yeast and, perhaps, other species within an ecosystem.

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Year:  2010        PMID： 20693605      PMCID： PMC2954037          DOI： 10.18632/aging.100186

Source DB:  PubMed          Journal:  Aging (Albany NY)        ISSN： 1945-4589            Impact factor:   5.682


  52 in total

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