Literature DB >> 20691796

Anatomical distribution of synovitis in knee osteoarthritis and its association with joint effusion assessed on non-enhanced and contrast-enhanced MRI.

F W Roemer1, M Kassim Javaid, A Guermazi, M Thomas, A Kiran, R Keen, L King, N K Arden.   

Abstract

PURPOSE: To describe the anatomical distribution of synovitis and its association with joint effusion on non-enhanced and contrast-enhanced (CE) MRI in patients with knee osteoarthritis (OA).
METHODS: Baseline MRI was performed at 1.5T using axial proton density (PD)-weighted (w) fat suppressed (fs) and axial and sagittal T1-w fs CE sequences. Synovial enhancement was scored in nine articular subregions. Maximum synovial enhancement was grouped as absent (0), equivocal (1) and definite (2 and 3). Effusion was scored from 0 to 3 on the axial sequences. We described the anatomical distribution of synovitis, its association with effusion and compared assessment of effusion on T1-w fs CE and PD fs sequences.
RESULTS: 111 subjects were included and examined by MRI. 89.2% of knees exhibited at least one subregion with a minimum grade 2 and 39.6% at the maximum of a grade 3. The commonest sites for definite synovitis were posterior to the posterior cruciate ligament (PCL) in 71.2% and in the suprapatellar region in 59.5% of all knees. On T1-w fs CE, 73.0% of knees showed any effusion. Definite synovitis in at least one location was present in 96.3% knees with an effusion and in 70.0% without an effusion. Higher grades of effusion were scored on the PD fs sequence.
CONCLUSION: Definite synovitis was present in the majority of knees with or without effusion with the commonest sites being posterior to the PCL and in the suprapatellar recess. Joint effusion as measured on PD fs images does not only represent effusion but also synovial thickening.
Copyright © 2010 Osteoarthritis Research Society International. Published by Elsevier Ltd. All rights reserved.

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Year:  2010        PMID: 20691796     DOI: 10.1016/j.joca.2010.07.008

Source DB:  PubMed          Journal:  Osteoarthritis Cartilage        ISSN: 1063-4584            Impact factor:   6.576


  60 in total

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Authors:  Carla R Scanzello; Brian McKeon; Bryan H Swaim; Edward DiCarlo; Eva U Asomugha; Veero Kanda; Anjali Nair; David M Lee; John C Richmond; Jeffrey N Katz; Mary K Crow; Steven R Goldring
Journal:  Arthritis Rheum       Date:  2011-02

Review 2.  An illustrative overview of semi-quantitative MRI scoring of knee osteoarthritis: lessons learned from longitudinal observational studies.

Authors:  F W Roemer; D J Hunter; M D Crema; C K Kwoh; E Ochoa-Albiztegui; A Guermazi
Journal:  Osteoarthritis Cartilage       Date:  2015-08-28       Impact factor: 6.576

3.  MRI-based volumetric assessment of joint effusion in knee osteoarthritis using proton density-weighted fat-suppressed and T1-weighted contrast-enhanced fat-suppressed sequences.

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4.  Early knee osteoarthritis prevalence is highest among middle-aged adult females with obesity based on new set of diagnostic criteria from a large sample cohort study in the Japanese general population.

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Review 6.  The role of synovitis in osteoarthritis pathogenesis.

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Journal:  J Thromb Haemost       Date:  2018-01-19       Impact factor: 5.824

9.  Synovitis in knee osteoarthritis: a precursor of disease?

Authors:  I Atukorala; C K Kwoh; A Guermazi; F W Roemer; R M Boudreau; M J Hannon; D J Hunter
Journal:  Ann Rheum Dis       Date:  2014-12-08       Impact factor: 19.103

10.  Double-inversion recovery with synthetic magnetic resonance: a pilot study for assessing synovitis of the knee joint compared to contrast-enhanced magnetic resonance imaging.

Authors:  Jisook Yi; Young Han Lee; Ho-Taek Song; Jin-Suck Suh
Journal:  Eur Radiol       Date:  2018-11-28       Impact factor: 5.315

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