Literature DB >> 20691443

On admission haemoglobin in patients with hip fracture.

D Kumar1, A N Mbako, A Riddick, S Patil, P Williams.   

Abstract

Several authors have identified on admission haemoglobin level as the most useful predictor of transfusion risk in patients with a hip fracture. A low postoperative haemoglobin unexplained by perioperative blood loss is not uncommon in these patients. The drop in haemoglobin after re-hydration prior to surgery should depend not only on the degree of dehydration but also on the amount of blood lost in the fracture.We could find no study in the English literature estimating the magnitude of this fall in haemoglobin after re-hydration prior to surgery.We conducted a prospective study to estimate the magnitude of fall in haemoglobin after rehydration prior to surgery by repeating the full blood count after at least 12 h of preoperative fluid resuscitation in 127 patients with hip fracture (75 consecutive at one centre and 52 consecutive at another).The average preoperative drop in haemoglobin was 2.23 gram/decilitre (g/dL) (p-value = 0.00) in subtrochanteric fractures, 1.1 g/dL (p-value = 0.001) in intertrochanteric fractures and 0.7 g/dL (p-value = 0.02) in intracapsular fractures. Fifteen patients with a haemoglobin level >9 g/dL on admission were found to have a haemoglobin level <9 g/dL on repeat test and were prevented from going to theatre without arrangements for perioperative transfusion during this study. Their predicted average postoperative haemoglobin without perioperative blood transfusion was calculated to be 6.5 g/dL.The on admission haemoglobin level was found to be falsely reassuring and could lead to a very low postoperative haemoglobin level. This could prove to be dangerous for many patients especially if remains undetected for several hours. We recommend that all patients with subtrochanteric fractures,and all patients with intertrochanteric or intracapsular fractures with a haemoglobin of less than 12 g/dL on admission have a repeat haemoglobin level performed prior to their surgery. 2010 Elsevier Ltd. All rights reserved.

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Year:  2011        PMID: 20691443     DOI: 10.1016/j.injury.2010.07.239

Source DB:  PubMed          Journal:  Injury        ISSN: 0020-1383            Impact factor:   2.586


  21 in total

1.  Perioperative factors associated with hidden blood loss in intertrochanteric fracture patients.

Authors:  Y Liu; Y Sun; L Fan; J Hao
Journal:  Musculoskelet Surg       Date:  2017-01-07

Review 2.  A systematic review of tranexamic acid in hip fracture surgery.

Authors:  Luke S Farrow; Toby O Smith; George P Ashcroft; Phyo K Myint
Journal:  Br J Clin Pharmacol       Date:  2016-09-20       Impact factor: 4.335

3.  Blood transfusion and risk of infection in frail elderly after hip fracture surgery: the TRIFE randomized controlled trial.

Authors:  Merete Gregersen; Else Marie Damsgaard; Lars Carl Borris
Journal:  Eur J Orthop Surg Traumatol       Date:  2015-02-18

4.  Predicting the need for blood transfusion in patients with hip fractures.

Authors:  Assaf Kadar; Ofir Chechik; Ely Steinberg; Evgeny Reider; Amir Sternheim
Journal:  Int Orthop       Date:  2013-02-05       Impact factor: 3.075

5.  The hidden blood loss in proximal femur fractures is sizeable and significant.

Authors:  John Stacey; Chelsea Bush; Thomas DiPasquale
Journal:  J Clin Orthop Trauma       Date:  2021-02-18

6.  Reducing unnecessary crossmatching for hip fracture patients by accounting for preoperative hemoglobin concentration.

Authors:  Raj M Amin; Varun Puvanesarajah; Yash P Chaudhry; Matthew J Best; Sandesh S Rao; Steven M Frank; Erik A Hasenboehler
Journal:  World J Orthop       Date:  2021-05-18

7.  Postoperative blood transfusion strategy in frail, anemic elderly patients with hip fracture: the TRIFE randomized controlled trial.

Authors:  Merete Gregersen; Lars C Borris; Else Marie Damsgaard
Journal:  Acta Orthop       Date:  2015-01-14       Impact factor: 3.717

8.  A prospective study about the preoperative total blood loss in older people with hip fracture.

Authors:  Jie-Zhou Wu; Peng-Cheng Liu; Wei Ge; Ming Cai
Journal:  Clin Interv Aging       Date:  2016-10-31       Impact factor: 4.458

9.  Comparison of intramedullary and extramedullary fixation of stable intertrochanteric fractures in the elderly: a prospective randomised controlled trial exploring hidden perioperative blood loss.

Authors:  Leyi Cai; Te Wang; Lu Di; Wei Hu; Jianshun Wang
Journal:  BMC Musculoskelet Disord       Date:  2016-11-15       Impact factor: 2.362

10.  Anemia on Admission Is an Independent Predictor of Long-Term Mortality in Hip Fracture Population: A Prospective Study With 2-Year Follow-Up.

Authors:  Licheng Zhang; Pengbin Yin; Houchen Lv; Anhua Long; Yuan Gao; Lihai Zhang; Peifu Tang
Journal:  Medicine (Baltimore)       Date:  2016-02       Impact factor: 1.889

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