Literature DB >> 20690687

Synthesis of indolequinones from bromoquinones and enamines mediated by Cu(OAc)2.H2O.

Martyn Inman1, Christopher J Moody.   

Abstract

A Cu(II)-mediated synthesis of indolequinones from the corresponding bromoquinones and enamines is reported. The key oxidative cyclization proceeds in good yield for a broad range of substrates and can be performed on a multigram scale, allowing access to biologically interesting structures.

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Year:  2010        PMID： 20690687     DOI： 10.1021/jo101071c

Source DB:  PubMed          Journal:  J Org Chem        ISSN： 0022-3263            Impact factor:   4.354


  6 in total

1.  Antitumour indolequinones: synthesis and activity against human pancreatic cancer cells.

Authors:  Martyn Inman; Andrea Visconti; Chao Yan; David Siegel; David Ross; Christopher J Moody
Journal:  Org Biomol Chem       Date:  2014-07-21       Impact factor: 3.876

2.  Ultrasound assisted one-pot synthesis of benzo-fused indole-4, 9-dinones from 1,4-naphthoquinone and α-aminoacetals.

Authors:  Quang H Luu; Jorge D Guerra; Cecilio M Castañeda; Manuel A Martinez; Jong Saunders; Benjamin A Garcia; Brenda V Gonzales; Anushritha R Aidunuthula; Shizue Mito
Journal:  Tetrahedron Lett       Date:  2016-04-16       Impact factor: 2.415

3.  A new and efficient procedure for the synthesis of hexahydropyrimidine-fused 1,4-naphthoquinones.

Authors:  Marcelo Isidoro P Reis; Vinícius R Campos; Jackson A L C Resende; Fernando C Silva; Vitor F Ferreira
Journal:  Beilstein J Org Chem       Date:  2015-07-22       Impact factor: 2.883

Review 4.  Hypoxia-activated prodrugs and redox-responsive nanocarriers.

Authors:  Yun Zeng; Jingwen Ma; Yonghua Zhan; Xinyi Xu; Qi Zeng; Jimin Liang; Xueli Chen
Journal:  Int J Nanomedicine       Date:  2018-10-18

5.  Copper(II)-Mediated Synthesis of Indolequinones from Bromoquinones and Enamines.

Authors:  Martyn Inman; Christopher J Moody
Journal:  European J Org Chem       Date:  2013-02-20

6.  Evaluation of the anti-inflammatory effects of synthesised tanshinone I and isotanshinone I analogues in zebrafish.

Authors:  Matthew J Foulkes; Faith H Tolliday; Katherine M Henry; Stephen A Renshaw; Simon Jones
Journal:  PLoS One       Date:  2020-10-06       Impact factor: 3.240
  6 in total

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