Literature DB >> 20689516

Association of cord blood platelet count and volume with hemoglobin in healthy term infants.

M Eskola1, S Juutistenaho, K Aranko, S Sainio, R Kekomäki.   

Abstract

OBJECTIVE: The aim of this study was to investigate relationships of cord blood cells in healthy term infants both from vaginal and Cesarean sections. STUDY
DESIGN: The study sample comprised 167 consecutive cord blood collections accepted for processing in an accredited cord blood bank. The effect of varying anticoagulant-to-blood ratio was excluded by standardizing the cell concentrations to reflect the values in native blood. Statistical analysis included descriptive statistics, simple linear regression analysis, Mann-Whitney U-test, cumulative frequency plots and Smirnov two-sample test. RESULT: As expected, hemoglobin correlated with red blood cell concentration. Interestingly, mean platelet volume was associated with hemoglobin, red blood cell concentration and hematocrit. The platelet count was inversely associated with the parameters.
CONCLUSION: The observed associations of cord blood hemoglobin with mean platelet volume and platelet count reflect the physiology of fetal hematopoiesis at term.

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Year:  2010        PMID: 20689516     DOI: 10.1038/jp.2010.95

Source DB:  PubMed          Journal:  J Perinatol        ISSN: 0743-8346            Impact factor:   2.521


  3 in total

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Journal:  Br J Clin Pharmacol       Date:  2016-01-12       Impact factor: 4.335

2.  A Physiologically-Based Pharmacokinetic Model to Predict Human Fetal Exposure for a Drug Metabolized by Several CYP450 Pathways.

Authors:  Maïlys De Sousa Mendes; Gabrielle Lui; Yi Zheng; Claire Pressiat; Deborah Hirt; Elodie Valade; Naïm Bouazza; Frantz Foissac; Stephane Blanche; Jean-Marc Treluyer; Saik Urien; Sihem Benaboud
Journal:  Clin Pharmacokinet       Date:  2017-05       Impact factor: 6.447

3.  Mean platelet volume reflect hematopoietic potency and correlated blood group o in cord blood from healthy newborn.

Authors:  Hye Ryun Lee; Jeong Su Park; Sue Shin; Eun Youn Roh; Jong Hyun Yoon; Eun Young Song; Byung Jae Kim; Ju Young Chang
Journal:  Biomed Res Int       Date:  2013-03-27       Impact factor: 3.411

  3 in total

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