| Literature DB >> 2068787 |
Abstract
Unique sequences, chromosomal subregions, or entire genomes can be specifically highlighted in metaphase or interphase cells by fluorescence in situ hybridization (FISH). This technique can be used to identify chromosomes, detect chromosomal abnormalities or determine the chromosomal location of specific sequences. FISH plays an increasingly important role in a variety of research areas, including cytogenetics, prenatal diagnosis, tumor biology, gene amplification and gene mapping.Entities:
Mesh:
Year: 1991 PMID: 2068787 DOI: 10.1016/0168-9525(91)90378-4
Source DB: PubMed Journal: Trends Genet ISSN: 0168-9525 Impact factor: 11.639