| Literature DB >> 20687603 |
Takayuki Kobatake1, Daishi Fujino, Suguru Yoshida, Hideki Yorimitsu, Koichiro Oshima.
Abstract
A concise and diversity-oriented route to trifluoromethylbenzo[b]furans has been devised. A variety of phenols are directly converted to the corresponding 2-methylthio-3-trifluoromethylbenzo[b]furans by new triflic-anhydride-mediated extended Pummerer annulation reactions with trifluoromethylketene dithioacetal monoxide. The methylthio group of the products undergoes further transformations, which increase the diversity of available trifluoromethylbenzo[b]furans.Entities:
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Year: 2010 PMID： 20687603 DOI： 10.1021/ja1030134
Source DB: PubMed Journal: J Am Chem Soc ISSN： 0002-7863 Impact factor: 15.419