Literature DB >> 20687048

Identifying targets to improve treatment in type 2 diabetes; the Groningen Initiative to aNalyse Type 2 diabetes Treatment (GIANTT) observational study.

Jaco Voorham1, Floor M Haaijer-Ruskamp, Klaas van der Meer, Dick de Zeeuw, Bruce H R Wolffenbuttel, Klaas Hoogenberg, Petra Denig.   

Abstract

PURPOSE: Assessment of quality of cardiometabolic risk management in diabetes in primary care.
METHODS: In a descriptive cohort study including 95 Dutch general practices, we assessed medication treatment in relation to the level of control for HbA1c, systolic blood pressure (SBP) and LDL-cholesterol (LDL-c) in 2007. We also applied a prospective measure of treatment quality by assessing treatment modifications in not well-controlled patients. In a subpopulation of 23 practices, we studied trends in these quality indicators from 2004 (2059 patients) to 2007 (2929 patients).
RESULTS: In 2007, averages for HbA1c, SBP and LDL-c were 6.9%, 142 mmHg and 2.3 mmol/l, respectively. Of the patients with an HbA1c >  8.5%, 16% were treated with one oral drug class and 50% used insulin. In 27% of these patients, therapy modification occurred subsequently. During the 4-year period, a slight decrease in average HbA1c was observed, but no changes in treatment level. In 2007, 56% of the patients had an SBP ≥ 140 mmHg, 19% of whom were not using antihypertensives. In the 13% with an SBP > 160 mmHg, 23% received a therapy modification. During the 4-year period, the average SBP decreased with 6 mmHg but the treatment level showed no substantial increase. In 2007, 39% had an LDL-c level ≥ 2.5 mmol/l, 49% of whom were not using statins. Of the patients with an LDL-c > 3.5 mmol/l, only 9% received a therapy modification.
CONCLUSIONS: The decreasing population averages of HbA1c, SBP and LDL-c values suggest improvement in quality of care. However, the relatively few therapy modifications observed in insufficiently controlled patients show room for improvement.
Copyright © 2010 John Wiley & Sons, Ltd.

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Year:  2010        PMID: 20687048     DOI: 10.1002/pds.2023

Source DB:  PubMed          Journal:  Pharmacoepidemiol Drug Saf        ISSN: 1053-8569            Impact factor:   2.890


  5 in total

1.  Medication Adherence Does Not Explain Black-White Differences in Cardiometabolic Risk Factor Control among Insured Patients with Diabetes.

Authors:  Jennifer Elston Lafata; Andrew J Karter; Patrick J O'Connor; Heather Morris; Julie A Schmittdiel; Scott Ratliff; Katherine M Newton; Marsha A Raebel; Ram D Pathak; Abraham Thomas; Melissa G Butler; Kristi Reynolds; Beth Waitzfelder; John F Steiner
Journal:  J Gen Intern Med       Date:  2016-02       Impact factor: 5.128

2.  A longitudinal study examining adherence to guidelines in diabetes care according to different definitions of adequacy and timeliness.

Authors:  Grigory Sidorenkov; Flora M Haaijer-Ruskamp; Dick de Zeeuw; Petra Denig
Journal:  PLoS One       Date:  2011-09-08       Impact factor: 3.240

3.  Differential effects of comorbidity on antihypertensive and glucose-regulating treatment in diabetes mellitus--a cohort study.

Authors:  Jaco Voorham; Flora M Haaijer-Ruskamp; Bruce H R Wolffenbuttel; Dick de Zeeuw; Ronald P Stolk; Petra Denig
Journal:  PLoS One       Date:  2012-06-05       Impact factor: 3.240

4.  Quality of care provided to diabetic patients attending primary health care centers in National Guard in Makkah Region, Saudi Arabia.

Authors:  Abdullah M AlZahrani; Osama S BinDajam; Sultan Ahmed AlGhamdi; Saad Salem AlQarni; Fayssal M Farahat
Journal:  J Family Med Prim Care       Date:  2022-06-30

5.  Population-based screen-detected type 2 diabetes mellitus is associated with less need for insulin therapy after 10 years.

Authors:  Rimke C Vos; Henk den Ouden; Lois A Daamen; Henk J G Bilo; Petra Denig; Guy E H M Rutten
Journal:  BMJ Open Diabetes Res Care       Date:  2020-03
  5 in total

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