Literature DB >> 20684940

[The current role of partial surgery as a strategy for functional preservation in laryngeal carcinoma].

Juan Pablo Rodrigo1, Andrés Coca-Pelaz, Carlos Suárez.   

Abstract

With the current advances and recent organ preservation protocols for intermediate or advanced stage laryngeal cancer, based on chemotherapy, the role of surgery seemed replaced except for surgical rescue of tumours not responding to these treatments, total laryngectomy being the surgical option. This type of non-surgical treatment is offered as a strategy for organ preservation, as opposed to total laryngectomy. However, we believe that there are two organ-preservation strategies, surgical and non-surgical. A wide spectrum of surgical techniques is available and such techniques lead to excellent results, both oncological and functional (speech and swallowing). The aim of this paper is to present options for organ-preserving surgery for laryngeal cancer. A review of surgical techniques available for functional preservation in cancer of the larynx at intermediate or advanced stage is presented. In addition to classic approaches such as vertical partial laryngectomy and horizontal or supraglottic laryngectomy, options for conservative laryngeal surgery have improved significantly over the past two decades. Minimally invasive surgery, transoral laser surgery, and supracricoid partial laryngectomy have become important laryngeal preservation approaches for patients with laryngeal cancer. Surgery must define its role in the multidisciplinary treatment of advanced cancers of the larynx, which at present often favours (chemo)radiotherapy protocols.
Copyright © 2010 Elsevier España, S.L. All rights reserved.

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Year:  2010        PMID: 20684940     DOI: 10.1016/j.otorri.2010.06.002

Source DB:  PubMed          Journal:  Acta Otorrinolaringol Esp        ISSN: 0001-6519


  5 in total

1.  Targeting CD133(+) laryngeal carcinoma cells with chemotherapeutic drugs and siRNA against ABCG2 mediated by thermo/pH-sensitive mesoporous silica nanoparticles.

Authors:  Xinmeng Qi; Dan Yu; Bo Jia; Chunshun Jin; Xueshibojie Liu; Xue Zhao; Guangxin Zhang
Journal:  Tumour Biol       Date:  2015-09-09

2.  Clinical outcomes and toxicity after exclusive versus postoperative radiotherapy in supraglottic cancer: new solutions for old problems? The case of stage III and IV disease.

Authors:  Loredana Costa; Sara Pedretti; Federica Foscarini; Marta Maddalo; Ludovica Pegurri; Nadia Pasinetti; Roberta Cavagnini; Stefano Ciccarelli; Sandro Tonoli; Stefano Maria Magrini; Michela Buglione
Journal:  Radiol Med       Date:  2015-08-01       Impact factor: 3.469

3.  Function preservation using transoral laser surgery for T2-T3 glottic cancer: oncologic, vocal, and swallowing outcomes.

Authors:  Giorgio Peretti; Cesare Piazza; Francesca Del Bon; Renzo Mora; Paola Grazioli; Diego Barbieri; Stefano Mangili; Piero Nicolai
Journal:  Eur Arch Otorhinolaryngol       Date:  2013-04-09       Impact factor: 2.503

4.  The prognostic implications of growth-related gene product β in laryngeal squamous cell carcinoma.

Authors:  Mingming Tang; Xinjiang Xu; Juanjuan Chen; Jiangfei Huang; Bin Jiang; Liang Han
Journal:  Oncol Lett       Date:  2017-07-18       Impact factor: 2.967

Review 5.  Functional Organ Preservation Surgery in Head and Neck Cancer: Transoral Robotic Surgery and Beyond.

Authors:  Wojciech Golusiński
Journal:  Front Oncol       Date:  2019-04-17       Impact factor: 6.244

  5 in total

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