Literature DB >> 20682215

Genetic and environmental risk factors for adolescent-onset substance use disorders.

Jacquelyn L Meyers1, Danielle M Dick.   

Abstract

Substance dependence disorders are chronic relapsing disorders with immense societal consequences. Twin and family studies have found that there are critical genetic and environmental components in the inheritance of substance use disorders, and modern advances in genetics are making it possible to identify specific variants that may predispose an individual to these disorders. Adolescence is a crucial period for initiation, experimentation, and the establishment of more regular patterns of use of alcohol and other drugs. Adolescent substance use is a known risk factor for the development of later alcohol and substance use problems, as well as related externalizing disorders such as antisocial personality disorder. Understanding the early risk factors and processes that make these youths vulnerable to substance use disorders is crucial to the development of effective strategies for prevention. This article reviews the genetic origins of adolescent substance use problems and the potential this field of research offers for prevention. Copyright (c) 2010 Elsevier Inc. All rights reserved.

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Year:  2010        PMID: 20682215      PMCID: PMC3661209          DOI: 10.1016/j.chc.2010.03.013

Source DB:  PubMed          Journal:  Child Adolesc Psychiatr Clin N Am        ISSN: 1056-4993


  50 in total

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5.  Longitudinal Relations among Adolescent Risk Behavior, Family Cohesion, Violence Exposure, and Mental Health in a National Sample.

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6.  Cannabis use disorder and male sex predict medical cannabis card status in a sample of high risk adolescents.

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7.  The adolescent brain at risk for substance use disorders: a review of functional MRI research on motor response inhibition.

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8.  Demographic and socioenvironmental predictors of premorbid marijuana use among patients with first-episode psychosis.

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9.  Genetic and environmental risk factors for illicit substance use and use disorders: Joint analysis of self and co-twin ratings.

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10.  Genetic and environmental predictors of latent trajectories of alcohol use from adolescence to adulthood: a male twin study.

Authors:  Marieke Wichers; Nathan A Gillespie; Kenneth S Kendler
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