| Literature DB >> 20681523 |
Eric Gayon1, Olivier Debleds, Marie Nicouleau, Frederic Lamaty, Arie van der Lee, Emmanuel Vrancken, Jean-Marc Campagne.
Abstract
An atom-economical and practical synthesis of cis-N-benzenesulfonamide acylaziridines through the Baldwin rearrangement of various N-benzenesulfonamide isoxazolines has been reported. A detailed experimental study revealed the beneficial effect of microwaves and pointed out the crucial role of the temperature in the reaction course. Moderate to good yields and excellent cis stereoselectivities were achieved for 13 examples.Entities:
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Year: 2010 PMID： 20681523 DOI： 10.1021/jo101273d
Source DB: PubMed Journal: J Org Chem ISSN： 0022-3263 Impact factor: 4.354