| Literature DB >> 20677173 |
L Baseggio1, A Traverse-Glehen, E Callet-Bauchu, D Morel, J P Magaud, F Berger, G Salles, P Felman.
Abstract
'Splenic red pulp lymphoma with numerous basophilic villous lymphocytes' (SRPL), recently described, is characterized by clinical, morphologic, immunologic, cytogenetic and molecular features distinct from SMZL/SLVL and HCL. In particular, the intensity of CD11c staining (expressed as fluorescence intensity -RFI-) in SRPL is significantly different from the RFI in SMZL/SLVL and HCL. Moreover the use of a scoring system based on the expression of CD11c, CD22, CD76, CD38 and CD27 appears to improve the differential diagnosis between SRPL and SMZL/SLVL and emphasizes that SRPL is an entity closed to but distinct from SMZL/SLVL.Entities:
Mesh:
Substances:
Year: 2011 PMID: 20677173 DOI: 10.1002/hon.957
Source DB: PubMed Journal: Hematol Oncol ISSN: 0278-0232 Impact factor: 5.271