Literature DB >> 20676439

Structural insights into substrate specificity and solvent tolerance in alcohol dehydrogenase ADH-'A' from Rhodococcus ruber DSM 44541.

Martin Karabec1, Andrzej Łyskowski, Katharina C Tauber, Georg Steinkellner, Wolfgang Kroutil, Gideon Grogan, Karl Gruber.   

Abstract

The structure of the alcohol dehydrogenase ADH-'A' from Rhodococcus ruber reveals possible reasons for its remarkable tolerance to organic co-solvents and suggests new directions for structure-informed mutagenesis to produce enzymes of altered substrate specificity or improved selectivity.

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Year:  2010        PMID： 20676439     DOI： 10.1039/c0cc00929f

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  8 in total

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Journal:  Acta Crystallogr F Struct Biol Commun       Date:  2014-05-24       Impact factor: 1.056

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Journal:  Aquat Biosyst       Date:  2012-02-02

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Journal:  Nat Commun       Date:  2019-05-15       Impact factor: 14.919

5.  Green and scalable synthesis of chiral aromatic alcohols through an efficient biocatalytic system.

Authors:  Meng-Nan Han; Xu-Ming Wang; Chao-Hong Pei; Chao Zhang; Zhidong Xu; Hong-Lei Zhang; Wei Li
Journal:  Microb Biotechnol       Date:  2020-05-31       Impact factor: 5.813

6.  Recombinant Enzymatic Redox Systems for Preparation of Aroma Compounds by Biotransformation.

Authors:  Viktor Varga; Vladimír Štefuca; Lenka Mihálová; Zdenko Levarski; Eva Struhárňanská; Jaroslav Blaško; Robert Kubinec; Pavel Farkaš; Vladimír Sitkey; Ján Turňa; Michal Rosenberg; Stanislav Stuchlík
Journal:  Front Microbiol       Date:  2021-06-24       Impact factor: 5.640

7.  Efficient biosynthesis of ethyl (R)-4-chloro-3-hydroxybutyrate using a stereoselective carbonyl reductase from Burkholderia gladioli.

Authors:  Xiang Chen; Zhi-Qiang Liu; Chao-Ping Lin; Yu-Guo Zheng
Journal:  BMC Biotechnol       Date:  2016-10-18       Impact factor: 2.563

8.  Reversal of Regioselectivity in Zinc-Dependent Medium-Chain Alcohol Dehydrogenase from Rhodococcus erythropolis toward Octanone Derivatives.

Authors:  Gaurao V Dhoke; Yunus Ensari; Dinc Yasat Hacibaloglu; Anna Gärtner; Anna Joëlle Ruff; Marco Bocola; Mehdi D Davari
Journal:  Chembiochem       Date:  2020-06-30       Impact factor: 3.164
  8 in total

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