Literature DB >> 20676108

Mechanical regulation of cell function with geometrically modulated elastomeric substrates.

Jianping Fu1, Yang-Kao Wang, Michael T Yang, Ravi A Desai, Xiang Yu, Zhijun Liu, Christopher S Chen.   

Abstract

We report the establishment of a library of micromolded elastomeric micropost arrays to modulate substrate rigidity independently of effects on adhesive and other material surface properties. We demonstrated that micropost rigidity impacts cell morphology, focal adhesions, cytoskeletal contractility and stem cell differentiation. Furthermore, early changes in cytoskeletal contractility predicted later stem cell fate decisions in single cells.

Entities:  

Mesh：

Substances：

Year:  2010        PMID： 20676108      PMCID： PMC3069358          DOI： 10.1038/nmeth.1487

Source DB:  PubMed          Journal:  Nat Methods        ISSN： 1548-7091            Impact factor:   28.547


  15 in total

Review 1.  Advances in the osteoblast lineage.

Authors:  J E Aubin
Journal:  Biochem Cell Biol       Date:  1998       Impact factor: 3.626

Review 2.  Mechanical signaling and the cellular response to extracellular matrix in angiogenesis and cardiovascular physiology.

Authors:  Donald E Ingber
Journal:  Circ Res       Date:  2002-11-15       Impact factor: 17.367

3.  Cells lying on a bed of microneedles: an approach to isolate mechanical force.

Authors:  John L Tan; Joe Tien; Dana M Pirone; Darren S Gray; Kiran Bhadriraju; Christopher S Chen
Journal:  Proc Natl Acad Sci U S A       Date:  2003-01-27       Impact factor: 11.205

4.  Cell shape, cytoskeletal tension, and RhoA regulate stem cell lineage commitment.

Authors:  Rowena McBeath; Dana M Pirone; Celeste M Nelson; Kiran Bhadriraju; Christopher S Chen
Journal:  Dev Cell       Date:  2004-04       Impact factor: 12.270

5.  Matrix elasticity directs stem cell lineage specification.

Authors:  Adam J Engler; Shamik Sen; H Lee Sweeney; Dennis E Discher
Journal:  Cell       Date:  2006-08-25       Impact factor: 41.582

6.  Cell locomotion and focal adhesions are regulated by substrate flexibility.

Authors:  R J Pelham; Y l Wang
Journal:  Proc Natl Acad Sci U S A       Date:  1997-12-09       Impact factor: 11.205

7.  The microenvironment of immobilized Arg-Gly-Asp peptides is an important determinant of cell adhesion.

Authors:  B T Houseman; M Mrksich
Journal:  Biomaterials       Date:  2001-05       Impact factor: 12.479

8.  Multilineage potential of adult human mesenchymal stem cells.

Authors:  M F Pittenger; A M Mackay; S C Beck; R K Jaiswal; R Douglas; J D Mosca; M A Moorman; D W Simonetti; S Craig; D R Marshak
Journal:  Science       Date:  1999-04-02       Impact factor: 47.728

Review 9.  Molecular regulation of adipogenesis.

Authors:  E D Rosen; B M Spiegelman
Journal:  Annu Rev Cell Dev Biol       Date:  2000       Impact factor: 13.827

10.  Nascent focal adhesions are responsible for the generation of strong propulsive forces in migrating fibroblasts.

Authors:  K A Beningo; M Dembo; I Kaverina; J V Small; Y L Wang
Journal:  J Cell Biol       Date:  2001-05-14       Impact factor: 10.539
View more
  367 in total

1.  Quantification of embryonic atrioventricular valve biomechanics during morphogenesis.

Authors:  Philip R Buskohl; Russell A Gould; Jonathan T Butcher
Journal:  J Biomech       Date:  2011-12-12       Impact factor: 2.712

Review 2.  Forcing stem cells to behave: a biophysical perspective of the cellular microenvironment.

Authors:  Yubing Sun; Christopher S Chen; Jianping Fu
Journal:  Annu Rev Biophys       Date:  2012-02-23       Impact factor: 12.981

3.  Measuring traction forces of motile dendritic cells on micropost arrays.

Authors:  Brendon G Ricart; Michael T Yang; Christopher A Hunter; Christopher S Chen; Daniel A Hammer
Journal:  Biophys J       Date:  2011-12-07       Impact factor: 4.033

4.  Enriching libraries of high-aspect-ratio micro- or nanostructures by rapid, low-cost, benchtop nanofabrication.

Authors:  Philseok Kim; Wilmer E Adorno-Martinez; Mughees Khan; Joanna Aizenberg
Journal:  Nat Protoc       Date:  2012-01-26       Impact factor: 13.491

5.  Hydrodynamic stretching of single cells for large population mechanical phenotyping.

Authors:  Daniel R Gossett; Henry T K Tse; Serena A Lee; Yong Ying; Anne G Lindgren; Otto O Yang; Jianyu Rao; Amander T Clark; Dino Di Carlo
Journal:  Proc Natl Acad Sci U S A       Date:  2012-04-30       Impact factor: 11.205

6.  Novel biomaterials to study neural stem cell mechanobiology and improve cell-replacement therapies.

Authors:  Phillip Kang; Sanjay Kumar; David Schaffer
Journal:  Curr Opin Biomed Eng       Date:  2017-09-22

7.  Intrafibrillar, bone-mimetic collagen mineralization regulates breast cancer cell adhesion and migration.

Authors:  Siyoung Choi; Jens Friedrichs; Young Hye Song; Carsten Werner; Lara A Estroff; Claudia Fischbach
Journal:  Biomaterials       Date:  2018-05-07       Impact factor: 12.479

8.  Bottom-up approaches in synthetic biology and biomaterials for tissue engineering applications.

Authors:  Mitchell S Weisenberger; Tara L Deans
Journal:  J Ind Microbiol Biotechnol       Date:  2018-03-19       Impact factor: 3.346

9.  Biomembrane-mimicking lipid bilayer system as a mechanically tunable cell substrate.

Authors:  Lena A Lautscham; Corey Y Lin; Vera Auernheimer; Christoph A Naumann; Wolfgang H Goldmann; Ben Fabry
Journal:  Biomaterials       Date:  2014-01-15       Impact factor: 12.479

10.  Global architecture of the F-actin cytoskeleton regulates cell shape-dependent endothelial mechanotransduction.

Authors:  Yue Shao; Jennifer M Mann; Weiqiang Chen; Jianping Fu
Journal:  Integr Biol (Camb)       Date:  2014-01-17       Impact factor: 2.192
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.