Literature DB >> 2067557

Rotenone induces aneuploidy, polyploidy and endoreduplication in cultured Chinese hamster cells.

K Matsumoto1, T Ohta.   

Abstract

The clastogenic potential of rotenone, an insecticide, was investigated in cultured Chinese hamster cells. Rotenone induced aneuploidy (hypodiploidy and hyperdiploidy), polyploidy, and endoreduplication, but not structural chromosome aberrations. The highest frequency of polyploidy and endoreduplication was 58.8% and 3.0%, respectively, when cells were treated with rotenone at 1.0 microgram/ml for 30 h.

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Year:  1991        PMID： 2067557     DOI： 10.1016/0165-7992(91)90058-c

Source DB:  PubMed          Journal:  Mutat Res        ISSN： 0027-5107            Impact factor:   2.433


  4 in total

1.  Involvement of p53 in cell death following cell cycle arrest and mitotic catastrophe induced by rotenone.

Authors:  António Pedro Gonçalves; Valdemar Máximo; Jorge Lima; Keshav K Singh; Paula Soares; Arnaldo Videira
Journal:  Biochim Biophys Acta       Date:  2011-01-09

2.  Sensitive period for the induction of endoreduplication by rotenone in cultured Chinese hamster cells.

Authors:  K Matsumoto; T Ohta
Journal:  Chromosoma       Date:  1992-12       Impact factor: 4.316

3.  ECVAM retrospective validation of in vitro micronucleus test (MNT).

Authors:  Raffaella Corvi; Silvio Albertini; Thomas Hartung; Sebastian Hoffmann; Daniela Maurici; Stefan Pfuhler; Jan van Benthem; Philippe Vanparys
Journal:  Mutagenesis       Date:  2008-03-07       Impact factor: 3.000

4.  DNA damage markers in dermal fibroblasts in vitro reflect chronological donor age.

Authors:  Mariëtte E C Waaijer; Eleonora Croco; Rudi G J Westendorp; P Eline Slagboom; John M Sedivy; Antonello Lorenzini; Andrea B Maier
Journal:  Aging (Albany NY)       Date:  2016-01       Impact factor: 5.682
  4 in total

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