| Literature DB >> 2067555 |
Abstract
The response of Pasteurella haemolytica to ultraviolet irradiation was determined. The results for survival show that P. haemolytica is very sensitive to UV-irradiation. This UV-sensitivity is similar to E. coli strains defective in UV repair mechanism(s). Analysis of the distribution of TCA insoluble versus TCA soluble [3H]thymine dimers in UV-irradiated DNA of P. haemolytica during a 2-h post-irradiation period indicates that the bacterium is deficient in an excision-repair system. These data suggest that P. haemolytica lacks some of the important mechanisms to repair UV-induced damage.Entities:
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Year: 1991 PMID: 2067555 DOI: 10.1016/0165-7992(91)90056-a
Source DB: PubMed Journal: Mutat Res ISSN: 0027-5107 Impact factor: 2.433