OBJECTIVE: To report the organization and early results of a visual inspection with acetic acid (VIA) screening program for cervical cancer prevention in Bangladesh. METHODS: Opportunistic VIA screening was offered by trained medical personnel to healthy women attending healthcare facilities in 44 districts. Colposcopy and/or directed biopsies were performed on VIA-positive women at Bangabandhu Sheikh Mujib Medical University (BSMMU) or medical college hospitals. The numbers of screened and VIA-positive women as well as the results of colposcopy, biopsy, and treatment of those with cervical intraepithelial neoplasia (CIN) attending BSMMU are reported. RESULTS: From January, 2005, to June, 2008, 104098 women underwent VIA screening. Among them, 5013 (4.8%) women were positive, of whom 4371 (87.2%) attended colposcopy clinics in different hospitals. Of the 2188 who underwent colposcopy at BSMMU, 157 were diagnosed with CIN 2-3 and 123 with invasive cancer. For 2065 women (excluding the cancer cases), results for sensitivity, specificity, and positive predictive value of VIA to detect CIN 2-3 lesions were 93.6%, 58.3%, and 15.6%, respectively. Almost half the women with CIN 2 or 3 lesions had treatment. CONCLUSION: A VIA-based program would facilitate the development of screening, diagnosis, and treatment of cervical neoplasia and improve awareness of cervical cancer prevention in Bangladesh.
OBJECTIVE: To report the organization and early results of a visual inspection with acetic acid (VIA) screening program for cervical cancer prevention in Bangladesh. METHODS: Opportunistic VIA screening was offered by trained medical personnel to healthy women attending healthcare facilities in 44 districts. Colposcopy and/or directed biopsies were performed on VIA-positive women at Bangabandhu Sheikh Mujib Medical University (BSMMU) or medical college hospitals. The numbers of screened and VIA-positive women as well as the results of colposcopy, biopsy, and treatment of those with cervical intraepithelial neoplasia (CIN) attending BSMMU are reported. RESULTS: From January, 2005, to June, 2008, 104098 women underwent VIA screening. Among them, 5013 (4.8%) women were positive, of whom 4371 (87.2%) attended colposcopy clinics in different hospitals. Of the 2188 who underwent colposcopy at BSMMU, 157 were diagnosed with CIN 2-3 and 123 with invasive cancer. For 2065 women (excluding the cancer cases), results for sensitivity, specificity, and positive predictive value of VIA to detect CIN 2-3 lesions were 93.6%, 58.3%, and 15.6%, respectively. Almost half the women with CIN 2 or 3 lesions had treatment. CONCLUSION: A VIA-based program would facilitate the development of screening, diagnosis, and treatment of cervical neoplasia and improve awareness of cervical cancer prevention in Bangladesh.
Authors: Ashrafun Nessa; Joya Shree Roy; Most Afroza Chowdhury; Quayuma Khanam; Romena Afroz; Charlotte Wistrand; Marcus Thuresson; Malin Thorsell; Isaac Shemer; Elisabeth Andrea Wikström Shemer Journal: BMJ Open Date: 2014-11-03 Impact factor: 2.692
Authors: J N I Vet; J L Kooijman; F C Henderson; F M Aziz; G Purwoto; H Susanto; I G D Surya; S Budiningsih; S Cornain; G J Fleuren; J B Trimbos; A A W Peters Journal: Br J Cancer Date: 2012-07-31 Impact factor: 7.640
Authors: Ashrafun Nessa; Charlotte Wistrand; Shirin Akter Begum; Marcus Thuresson; Isaac Shemer; Malin Thorsell; Elisabeth Andrea Wikström Shemer Journal: Int J Gynecol Cancer Date: 2014-02 Impact factor: 3.437
Authors: Geneva A DeGregorio; Leslie S Bradford; Simon Manga; Pius M Tih; Richard Wamai; Rebecca Ogembo; Zacharie Sando; Yuxin Liu; Constance Schwaiger; Sowmya R Rao; Karen Kalmakis; Lisa Kennedy Sheldon; Kathleen Nulah; Edith Welty; Thomas Welty; Javier Gordon Ogembo Journal: PLoS One Date: 2016-06-09 Impact factor: 3.240