Literature DB >> 20671762

Genetic diseases: new tricks for known drugs.

Charlotte Harrison.   

Abstract

Entities:  

Year:  2010        PMID： 20671762     DOI： 10.1038/nrd3232

Source DB:  PubMed          Journal:  Nat Rev Drug Discov        ISSN： 1474-1776            Impact factor:   84.694


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  2 in total

1.  An autophagy-enhancing drug promotes degradation of mutant alpha1-antitrypsin Z and reduces hepatic fibrosis.

Authors:  Tunda Hidvegi; Michael Ewing; Pamela Hale; Christine Dippold; Caroline Beckett; Carolyn Kemp; Nicholas Maurice; Amitava Mukherjee; Christina Goldbach; Simon Watkins; George Michalopoulos; David H Perlmutter
Journal:  Science       Date:  2010-06-03       Impact factor: 47.728

2.  Inhibition of glucosylceramide accumulation results in effective blockade of polycystic kidney disease in mouse models.

Authors:  Thomas A Natoli; Laurie A Smith; Kelly A Rogers; Bing Wang; Svetlana Komarnitsky; Yeva Budman; Alexei Belenky; Nikolay O Bukanov; William R Dackowski; Hervé Husson; Ryan J Russo; James A Shayman; Steven R Ledbetter; John P Leonard; Oxana Ibraghimov-Beskrovnaya
Journal:  Nat Med       Date:  2010-06-20       Impact factor: 53.440
  2 in total

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