Literature DB >> 20670160

Mesenchymal stem cells: a new promise in anticancer therapy.

Sabino Ciavarella1, Massimo Dominici, Franco Dammacco, Franco Silvestris.   

Abstract

Novel cell-based and gene therapies represent promising approaches for the treatment of incurable diseases, including cancer. Following the success of the hematopoietic stem cell-based transplantation, other populations of adult progenitor cells, including mesenchymal stem cells (MSCs), have been identified as powerful therapeutic tools in humans. The intrinsic capability of MSCs to migrate toward injured tissues emphasizes their suitability to deliver anticancer agents for new clinical applications in addition to the tissue repairing capacity. Here, we revisit the experimental history of MSCs, the most exciting features of their biology in keeping with their promising applications in cell-based therapeutic strategies for cancer treatment.

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Year:  2010        PMID: 20670160     DOI: 10.1089/scd.2010.0223

Source DB:  PubMed          Journal:  Stem Cells Dev        ISSN: 1547-3287            Impact factor:   3.272


  17 in total

1.  The role of CCL5 in the ability of adipose tissue-derived mesenchymal stem cells to support repair of ischemic regions.

Authors:  Kenichi Kimura; Masumi Nagano; Georgina Salazar; Toshiharu Yamashita; Ikki Tsuboi; Hajime Mishima; Shonosuke Matsushita; Fujio Sato; Kenji Yamagata; Osamu Ohneda
Journal:  Stem Cells Dev       Date:  2013-12-14       Impact factor: 3.272

2.  Bone marrow derived mesenchymal stem/stromal cells transduced with full length human TRAIL repress the growth of rhabdomyosarcoma cells in vitro.

Authors:  Helga Barti-Juhasz; Rudolf Mihalik; Katalin Nagy; Giulia Grisendi; Massimo Dominici; Istvan Petak
Journal:  Haematologica       Date:  2011-03       Impact factor: 9.941

3.  A peculiar molecular profile of umbilical cord-mesenchymal stromal cells drives their inhibitory effects on multiple myeloma cell growth and tumor progression.

Authors:  Sabino Ciavarella; Anna Caselli; Antonella Valentina Tamma; Annalisa Savonarola; Giuseppe Loverro; Roberto Paganelli; Marco Tucci; Franco Silvestris
Journal:  Stem Cells Dev       Date:  2015-03-11       Impact factor: 3.272

4.  Umbilical cord blood-derived mesenchymal stem cells inhibit, but adipose tissue-derived mesenchymal stem cells promote, glioblastoma multiforme proliferation.

Authors:  Keiko Akimoto; Kenichi Kimura; Masumi Nagano; Shingo Takano; Georgina To'a Salazar; Toshiharu Yamashita; Osamu Ohneda
Journal:  Stem Cells Dev       Date:  2013-02-04       Impact factor: 3.272

Review 5.  Mesenchymal stem cells as a vector for the inflammatory prostate microenvironment.

Authors:  W Nathaniel Brennen; Samuel R Denmeade; John T Isaacs
Journal:  Endocr Relat Cancer       Date:  2013-08-23       Impact factor: 5.678

6.  Mesenchymal stromal cells primed with paclitaxel provide a new approach for cancer therapy.

Authors:  Augusto Pessina; Arianna Bonomi; Valentina Coccè; Gloria Invernici; Stefania Navone; Loredana Cavicchini; Francesca Sisto; Maura Ferrari; Lucia Viganò; Alberta Locatelli; Emilio Ciusani; Graziella Cappelletti; Daniele Cartelli; Caruso Arnaldo; Eugenio Parati; Giovanni Marfia; Roberto Pallini; Maria Laura Falchetti; Giulio Alessandri
Journal:  PLoS One       Date:  2011-12-20       Impact factor: 3.240

7.  Journey of mesenchymal stem cells for homing: strategies to enhance efficacy and safety of stem cell therapy.

Authors:  Sung Keun Kang; Il Seob Shin; Myung Soon Ko; Jung Youn Jo; Jeong Chan Ra
Journal:  Stem Cells Int       Date:  2012-06-13       Impact factor: 5.443

8.  Altered features and increased chemosensitivity of human breast cancer cells mediated by adipose tissue-derived mesenchymal stromal cells.

Authors:  Lucia Kucerova; Svetlana Skolekova; Miroslava Matuskova; Martin Bohac; Zuzana Kozovska
Journal:  BMC Cancer       Date:  2013-11-09       Impact factor: 4.430

9.  MiR-7 promotes epithelial cell transformation by targeting the tumor suppressor KLF4.

Authors:  Karla F Meza-Sosa; Erick I Pérez-García; Nohemí Camacho-Concha; Oswaldo López-Gutiérrez; Gustavo Pedraza-Alva; Leonor Pérez-Martínez
Journal:  PLoS One       Date:  2014-09-02       Impact factor: 3.240

10.  Pathogen-free, plasma-poor platelet lysate and expansion of human mesenchymal stem cells.

Authors:  Paola Iudicone; Daniela Fioravanti; Giuseppina Bonanno; Michelina Miceli; Claudio Lavorino; Pierangela Totta; Luigi Frati; Marianna Nuti; Luca Pierelli
Journal:  J Transl Med       Date:  2014-01-27       Impact factor: 5.531

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