| Literature DB >> 2066549 |
S Orii1, T Sugai, O Nakano, H Yoshinari, S Sato.
Abstract
A 19-year-old man with a documented 2-year history of Crohn's disease abruptly developed leukopenia and thrombocytopenia. A diagnosis of acute promyelocytic leukemia was established by bone marrow cytology. Chromosomal analysis of bone marrow aspirate revealed aberrations of no. 8 trisomy and translocation between no. 15 and no. 17 [46,XY,t(15q+,17q-)/47,XY,+8,t(15q+,17q-)]. Nine cases of Crohn's disease complicated by leukemia have been reported, including the present one; once again, a relationship between Crohn's disease and leukemia is suggested.Entities:
Mesh:
Year: 1991 PMID: 2066549
Source DB: PubMed Journal: J Clin Gastroenterol ISSN: 0192-0790 Impact factor: 3.062