| Literature DB >> 20664606 |
Keiichiro Motohashi1, Motoki Takagi, Hideki Yamamura, Masayuki Hayakawa, Kazuo Shin-ya.
Abstract
A new 1,1-dichlorocyclopropane-containing angucycline, JBIR-88 (1), and a new butenolide, JBIR-89 (2), respectively, were isolated from the fermentation broths of two lichen-derived actinomycetes identified as a new species of Streptomyces (strains RI104-LiC106 and RI104-LiB101) using phylogenetic methods. The structures of 1 and 2 were elucidated on the basis of 1D and 2D NMR spectroscopy and MS analyses. Compound 1 showed cytotoxic activities against cancer cells and antimicrobial activity against Micrococcus luteus.Entities:
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Year: 2010 PMID： 20664606 DOI： 10.1038/ja.2010.94
Source DB: PubMed Journal: J Antibiot (Tokyo) ISSN： 0021-8820 Impact factor: 2.649