PURPOSE: This study examined quality of life, transplant-related concerns, and depressive symptoms and their demographic and medical correlates at 1 to 3 years following hematopoietic stem cell transplantation (HSCT). METHODS: HSCT survivors (N=406) completed telephone-administered questionnaires that assessed demographic variables, functional status, quality of life, transplant-related concerns, and depressive symptoms. RESULTS: The most prevalent concerns among HSCT survivors included physical symptoms (e.g., fatigue and pain), maintaining current health status and employment, changes in appearance, and lack of sexual interest and satisfaction. In addition, almost one-third (32%) of survivors age 40 years and younger reported concern about their ability to have children. Unemployed survivors and those with lower incomes and worse functional status were more likely to experience poorer quality of life in multiple domains. Fifteen percent of the sample reported moderate to severe depressive symptoms, and these symptoms were higher among allogeneic transplant recipients and those with lower functional status. CONCLUSIONS: Results suggest that interventions are needed to address physical symptoms, coping with an uncertain future, infertility, and sexual issues during the early phase of HSCT survivorship.
PURPOSE: This study examined quality of life, transplant-related concerns, and depressive symptoms and their demographic and medical correlates at 1 to 3 years following hematopoietic stem cell transplantation (HSCT). METHODS: HSCT survivors (N=406) completed telephone-administered questionnaires that assessed demographic variables, functional status, quality of life, transplant-related concerns, and depressive symptoms. RESULTS: The most prevalent concerns among HSCT survivors included physical symptoms (e.g., fatigue and pain), maintaining current health status and employment, changes in appearance, and lack of sexual interest and satisfaction. In addition, almost one-third (32%) of survivors age 40 years and younger reported concern about their ability to have children. Unemployed survivors and those with lower incomes and worse functional status were more likely to experience poorer quality of life in multiple domains. Fifteen percent of the sample reported moderate to severe depressive symptoms, and these symptoms were higher among allogeneic transplant recipients and those with lower functional status. CONCLUSIONS: Results suggest that interventions are needed to address physical symptoms, coping with an uncertain future, infertility, and sexual issues during the early phase of HSCT survivorship.
Authors: S Bieri; E Roosnek; C Helg; F Verholen; D Robert; B Chapuis; J Passweg; R Miralbell; Y Chalandon Journal: Bone Marrow Transplant Date: 2008-08-18 Impact factor: 5.483
Authors: M F M Gielissen; A V M Schattenberg; C A H H V M Verhagen; M J Rinkes; M E J Bremmers; G Bleijenberg Journal: Bone Marrow Transplant Date: 2007-03-19 Impact factor: 5.483
Authors: Michelle M Bishop; Jennifer L Beaumont; Elizabeth A Hahn; David Cella; Michael A Andrykowski; Marianne J Brady; Mary M Horowitz; Kathleen A Sobocinski; J Douglas Rizzo; John R Wingard Journal: J Clin Oncol Date: 2007-04-10 Impact factor: 44.544
Authors: Jean C Yi; Brie Sullivan; Wendy M Leisenring; Navneet S Majhail; Heather Jim; Alison Loren; Joseph Uberti; Victoria Whalen; Mary E D Flowers; Stephanie J Lee; Katie Maynard; Karen L Syrjala Journal: Biol Blood Marrow Transplant Date: 2020-06-26 Impact factor: 5.742
Authors: Karen L Syrjala; Jean C Yi; Samantha B Artherholt; Joan M Romano; Marie-Laure Crouch; Allison S Fiscalini; Mark T Hegel; Mary E D Flowers; Paul J Martin; Wendy M Leisenring Journal: J Cancer Surviv Date: 2018-05-05 Impact factor: 4.442
Authors: Anna Barata; Brian D Gonzalez; Steven K Sutton; Brent J Small; Paul B Jacobsen; Teresa Field; Hugo Fernandez; Heather Sl Jim Journal: J Health Psychol Date: 2016-04-22
Authors: Heather S L Jim; Bryan Evans; Jiyeon M Jeong; Brian D Gonzalez; Laura Johnston; Ashley M Nelson; Shelli Kesler; Kristin M Phillips; Anna Barata; Joseph Pidala; Oxana Palesh Journal: Biol Blood Marrow Transplant Date: 2014-04-18 Impact factor: 5.742
Authors: Margaret Bevans; Areej El-Jawahri; D Kathryn Tierney; Lori Wiener; William A Wood; Flora Hoodin; Erin E Kent; Paul B Jacobsen; Stephanie J Lee; Matthew M Hsieh; Ellen M Denzen; Karen L Syrjala Journal: Biol Blood Marrow Transplant Date: 2016-09-19 Impact factor: 5.742
Authors: A M J Braamse; B van Meijel; O Visser; P C Huijgens; A T F Beekman; J Dekker Journal: Bone Marrow Transplant Date: 2013-10-07 Impact factor: 5.483
Authors: Jessica P Hwang; Aimee K Roundtree; Sergio A Giralt; Maria Suarez-Almazor Journal: BMJ Support Palliat Care Date: 2012-08-03 Impact factor: 3.568