PURPOSE: Weaning from prolonged mechanical ventilation may be associated with mental discomfort. It is not known whether such discomfort is linked with the development of post-traumatic stress disorder (PTSD). Accordingly, we investigated whether PTSD occurs in patients after weaning from prolonged ventilation. We also determined whether administering a questionnaire would identify patients at risk for developing PTSD. METHODS: A prospective longitudinal study of patients transferred to a long-term acute-care hospital for weaning from prolonged ventilation was undertaken: 72 patients were studied 1 week after weaning, and 41 patients were studied again 3 months later. An experienced psychologist conducted a structured clinical interview 3 months after weaning to establish a diagnosis of PTSD. To assess for the presence of PTSD-related symptoms, the post-traumatic stress syndrome (PTSS-10) questionnaire was administered 1 week after weaning and 3 months later. RESULTS: The psychologist diagnosed PTSD in 12% of patients 3 months after ventilator weaning. Patients who developed PTSD were more likely to have a previous history of psychiatric disorders (P < 0.02). A PTSS-10 score >20 one week after weaning reliably identified patients who were diagnosed with PTSD 3 months later: sensitivity 1.0; specificity 0.76; area under the receiver-operating characteristic curve 0.91. CONCLUSION: PTSD was diagnosed in 12% of patients who were weaned from prolonged ventilation. A PTSS-10 score >20 one week after weaning identified patients diagnosed with PTSD 3 months later. This finding suggests that a simple questionnaire administered before hospital discharge can identify patients at risk for developing PTSD.
PURPOSE: Weaning from prolonged mechanical ventilation may be associated with mental discomfort. It is not known whether such discomfort is linked with the development of post-traumatic stress disorder (PTSD). Accordingly, we investigated whether PTSD occurs in patients after weaning from prolonged ventilation. We also determined whether administering a questionnaire would identify patients at risk for developing PTSD. METHODS: A prospective longitudinal study of patients transferred to a long-term acute-care hospital for weaning from prolonged ventilation was undertaken: 72 patients were studied 1 week after weaning, and 41 patients were studied again 3 months later. An experienced psychologist conducted a structured clinical interview 3 months after weaning to establish a diagnosis of PTSD. To assess for the presence of PTSD-related symptoms, the post-traumatic stress syndrome (PTSS-10) questionnaire was administered 1 week after weaning and 3 months later. RESULTS: The psychologist diagnosed PTSD in 12% of patients 3 months after ventilator weaning. Patients who developed PTSD were more likely to have a previous history of psychiatric disorders (P < 0.02). A PTSS-10 score >20 one week after weaning reliably identified patients who were diagnosed with PTSD 3 months later: sensitivity 1.0; specificity 0.76; area under the receiver-operating characteristic curve 0.91. CONCLUSION:PTSD was diagnosed in 12% of patients who were weaned from prolonged ventilation. A PTSS-10 score >20 one week after weaning identified patients diagnosed with PTSD 3 months later. This finding suggests that a simple questionnaire administered before hospital discharge can identify patients at risk for developing PTSD.
Authors: Dimitry S Davydow; Jeneen M Gifford; Sanjay V Desai; Dale M Needham; O Joseph Bienvenu Journal: Gen Hosp Psychiatry Date: 2008-07-30 Impact factor: 3.238
Authors: Timothy D Girard; Ayumi K Shintani; James C Jackson; Sharon M Gordon; Brenda T Pun; Melinda S Henderson; Robert S Dittus; Gordon R Bernard; E Wesley Ely Journal: Crit Care Date: 2007 Impact factor: 9.097
Authors: Maria Deja; Claudia Denke; Steffen Weber-Carstens; Jürgen Schröder; Christian E Pille; Frank Hokema; Konrad J Falke; Udo Kaisers Journal: Crit Care Date: 2006 Impact factor: 9.097
Authors: Kimberly R Boer; Oddeke van Ruler; Arnold A P van Emmerik; Mirjam A Sprangers; Sophia E de Rooij; Margreeth B Vroom; Corianne A J M de Borgie; Marja A Boermeester; Johannes B Reitsma Journal: Intensive Care Med Date: 2008-01-16 Impact factor: 17.440
Authors: Jordin K Shelley; Jacob W Roden-Foreman; David Vier; Evan Elizabeth McShan; Monica M Bennett; Alan L Jones; Ann Marie Warren Journal: Proc (Bayl Univ Med Cent) Date: 2020-09-02
Authors: David G Cohen; Jason D Christie; Brian J Anderson; Joshua M Diamond; Ryan P Judy; Rupal J Shah; Edward Cantu; Scarlett L Bellamy; Nancy P Blumenthal; Ejigayehu Demissie; Ramona O Hopkins; Mark E Mikkelsen Journal: Ann Am Thorac Soc Date: 2014-05
Authors: Christopher E Cox; Laura S Porter; Catherine L Hough; Douglas B White; Jeremy M Kahn; Shannon S Carson; James A Tulsky; Francis J Keefe Journal: Intensive Care Med Date: 2012-04-18 Impact factor: 17.440
Authors: Fabienne D Simonis; Ary Serpa Neto; Jan M Binnekade; Annemarije Braber; Karina C M Bruin; Rogier M Determann; Geert-Jan Goekoop; Jeroen Heidt; Janneke Horn; Gerard Innemee; Evert de Jonge; Nicole P Juffermans; Peter E Spronk; Lotte M Steuten; Pieter Roel Tuinman; Rob B P de Wilde; Marijn Vriends; Marcelo Gama de Abreu; Paolo Pelosi; Marcus J Schultz Journal: JAMA Date: 2018-11-13 Impact factor: 56.272
Authors: Louise Rose; Marcus J Schultz; Chris R Cardwell; Philippe Jouvet; Danny F McAuley; Bronagh Blackwood Journal: Cochrane Database Syst Rev Date: 2014-06-10