Literature DB >> 20661107

Polymorphism in the p2x7 gene increases susceptibility to extrapulmonary tuberculosis in Turkish children.

Deniz Tekin1, Zeliha Kayaalti, Nazan Dalgic, Erkan Cakir, Tulin Soylemezoglu, Busra Isin Kutlubay, Betul Aydin Kilic.   

Abstract

The P2X7 gene polymorphisms have been linked to increased risk for pulmonary and extrapulmonary tuberculosis in some populations. In this study, the genotype and allelic frequencies 1513A-->C variant within the P2X7 gene was significantly higher than in the healthy controls (P = 0.035, P = 0.041). This is the first study demonstrating that the 1513A-->C polymorphism is associated with extrapulmonary tuberculosis in children.

Entities:  

Mesh：

Substances：

Year:  2010        PMID： 20661107     DOI： 10.1097/INF.0b013e3181d9932e

Source DB:  PubMed          Journal:  Pediatr Infect Dis J        ISSN： 0891-3668            Impact factor:   2.129


  13 in total

Review 1.  Molecular and functional properties of P2X receptors--recent progress and persisting challenges.

Authors:  Karina Kaczmarek-Hájek; Eva Lörinczi; Ralf Hausmann; Annette Nicke
Journal:  Purinergic Signal       Date:  2012-05-01       Impact factor: 3.765

2.  The association between C-159T polymorphism in CD14 gene and susceptibility to tuberculosis: a meta-analysis.

Authors:  Qing Yuan; Huifang Chen; Xueyan Zheng; Xiaming Chen; Qun Li; Yanping Zhang; Xiaorong Zhang; Tingli Shi; Junhua Zhou; Qing Chen; Shouyi Yu
Journal:  Mol Biol Rep       Date:  2014-08-05       Impact factor: 2.316

3.  Adenosine modulates Toll-like receptor function: basic mechanisms and translational opportunities.

Authors:  Melanie R Power Coombs; Mirjam E Belderbos; Leighanne C Gallington; Louis Bont; Ofer Levy
Journal:  Expert Rev Anti Infect Ther       Date:  2011-02       Impact factor: 5.091

Review 4.  Transcriptional control mechanisms associated with the nucleotide receptor P2X7, a critical regulator of immunologic, osteogenic, and neurologic functions.

Authors:  Lisa Y Lenertz; Monica L Gavala; Yiming Zhu; Paul J Bertics
Journal:  Immunol Res       Date:  2011-05       Impact factor: 2.829

5.  P2X7R Gene Polymorphisms are Associated with Increased Risk of Pulmonary Tuberculosis in the Tibetan Chinese Population.

Authors:  Xikai Zhu; Wen Guo; Guoxia Ren; Xue He; Qunying Hu; Yuan Zhang; Longli Kang; Dongya Yuan; Tianbo Jin
Journal:  Am J Trop Med Hyg       Date:  2016-09-26       Impact factor: 2.345

Review 6.  P2RX7 at the Host-Pathogen Interface of Infectious Diseases.

Authors:  Alexandra Y Soare; Tracey L Freeman; Alice K Min; Hagerah S Malik; Elizabeth O Osota; Talia H Swartz
Journal:  Microbiol Mol Biol Rev       Date:  2021-01-13       Impact factor: 11.056

Review 7.  The role of the P2X₇ receptor in infectious diseases.

Authors:  Catherine M Miller; Nicola R Boulter; Stephen J Fuller; Alana M Zakrzewski; Michael P Lees; Bernadette M Saunders; James S Wiley; Nicholas C Smith
Journal:  PLoS Pathog       Date:  2011-11-10       Impact factor: 6.823

8.  A meta-analysis of P2X7 gene-762T/C polymorphism and pulmonary tuberculosis susceptibility.

Authors:  Lingling Yi; Dan Cheng; Huimin Shi; Xiaorong Huo; Kan Zhang; Guohua Zhen
Journal:  PLoS One       Date:  2014-05-08       Impact factor: 3.240

9.  Pulmonary infection with hypervirulent Mycobacteria reveals a crucial role for the P2X7 receptor in aggressive forms of tuberculosis.

Authors:  Eduardo P Amaral; Simone C M Ribeiro; Verônica R Lanes; Fabrício M Almeida; Marcelle R M de Andrade; Caio Cesar Barbosa Bomfim; Erika M Salles; Karina R Bortoluci; Robson Coutinho-Silva; Mario H Hirata; José M Alvarez; Elena B Lasunskaia; Maria Regina D'Império-Lima
Journal:  PLoS Pathog       Date:  2014-07-03       Impact factor: 6.823

10.  Single Nucleotide Polymorphisms in P2X7 Gene Are Associated with Serum Immunoglobulin G Responses to Mycobacterium tuberculosis in Tuberculosis Patients.

Authors:  Jiangdong Wu; Lijun Lu; Le Zhang; Yulei Ding; Fang Wu; Weize Zuo; Wanjiang Zhang
Journal:  Dis Markers       Date:  2015-12-20       Impact factor: 3.434
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.