Literature DB >> 20657121

Tophi as first manifestation of gout.

Sankha Koley1, Atul Salodkar, Sanjiv Choudhary, Arvind Bhake, Kailash Singhania, Manoj Choudhury.   

Abstract

Chronic tophaceous gout classically occurs after 10 years or more of recurrent polyarticular gout. However, tophi can also occur as first sign of the disorder. Here we report a 20-year-old male presenting with multiple subcutaneous nodules on bilateral feet and toes, left palm, right elbow, helix of left ear since last one and half year prior to any other manifestation of gout. He was having mild intermittent arthritis since last six months. Fine Needle Aspiration Cytology of one tophus showed monosodium urate crystals, which are pathognomonic for gout. His serum uric acid was normal and ultrasound revealed bilateral nephrocalcinosis. So far as we know, this is the first case report from India, demonstrating tophi as the initial clinical presentation of gout.

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Year:  2010        PMID: 20657121     DOI: 10.4103/0378-6323.66593

Source DB:  PubMed          Journal:  Indian J Dermatol Venereol Leprol        ISSN: 0378-6323            Impact factor:   2.545


  7 in total

1.  New onset of very large tophi in a patient after kidney transplantation.

Authors:  Mohammad Hasan Alemzadeh-Ansari; Mohammad Javad Alemzadeh-Ansari
Journal:  Clin Med Res       Date:  2011-05-11

2.  Metabolic characteristics and renal dysfunction in 65 patients with tophi prior to gout.

Authors:  Chuan-Chin Lu; Shyi-Kuen Wu; Wei-Sheng Chung; Liang-Hung Lin; Ta-Wei Hung; Chih-Jung Yeh
Journal:  Clin Rheumatol       Date:  2017-05-10       Impact factor: 2.980

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Authors:  Athina Fonia; Bertrand Richert
Journal:  Skin Appendage Disord       Date:  2019-12-18

Review 4.  Knuckle lesions in inherited and acquired disorders.

Authors:  Keshavmurthy A Adya; Arun C Inamadar; Aparna Palit; Ragunatha Shivanna
Journal:  Indian Dermatol Online J       Date:  2021-11-22

5.  Fine-needle aspiration cytology of periarticular nodule - Atypical presentation of gouty tophi: A report of two cases.

Authors:  Durre Aden; Prajwala Gupta; Minakshi Bharadwaj
Journal:  Cytojournal       Date:  2022-08-05       Impact factor: 2.345

6.  Tophus of the Pubis Bone: A Case Report.

Authors:  Chetan Prakash Oswal; Ashwin Samant; Sunil Shahane; Aditya Pathak
Journal:  J Orthop Case Rep       Date:  2013 Oct-Dec

7.  Gouty tophus without gout attacks treated using a reversed digital artery flap.

Authors:  Yukako Okuhara; Keisuke Shimbo; Shogo Nagamatsu; Kazunori Yokota
Journal:  Case Reports Plast Surg Hand Surg       Date:  2020-04-23
  7 in total

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