Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 The Bermuda Triangle of cocaine-induced neuroadaptations.

Literature DB >> 20655604

The Bermuda Triangle of cocaine-induced neuroadaptations.

Abstract

Activation of medium spiny neurons (MSNs) of the nucleus accumbens is critical for goal-directed behaviors including cocaine seeking. Studies in cocaine-experienced rodents have revealed three major categories of neuroadaptations that influence the ability of glutamate inputs to activate MSNs: changes in synaptic AMPA receptor levels, changes in extracellular non-synaptic glutamate levels and changes in MSN intrinsic membrane excitability. Most studies have focused on one of these adaptations. This review will consider the possibility that they are causally related and speculate about how time-dependent changes in their interactions may regulate MSN output during early and late withdrawal from repeated cocaine exposure. Copyright 2010 Elsevier Ltd. All rights reserved.

Entities: Chemical Disease Gene Species

Mesh：

Substances：

Year: 2010 PMID： 20655604 PMCID： PMC2935206 DOI： 10.1016/j.tins.2010.06.003

Source DB: PubMed Journal: Trends Neurosci ISSN： 0166-2236 Impact factor: 13.837

89 in total

Review 1. The role of accumbal hypoactivity in cocaine addiction.

Authors: L L Peoples; A V Kravitz; K Guillem
Journal: ScientificWorldJournal Date: 2007-11-02

Review 2. The effects of cocaine: a shifting target over the course of addiction.

Authors: Linda J Porrino; Hilary R Smith; Michael A Nader; Thomas J R Beveridge
Journal: Prog Neuropsychopharmacol Biol Psychiatry Date: 2007-09-04 Impact factor: 5.067

Review 3. The structural basis for mapping behavior onto the ventral striatum and its subdivisions.

Authors: Gloria E Meredith; Brian A Baldo; Matthew E Andrezjewski; Ann E Kelley
Journal: Brain Struct Funct Date: 2008-02-07 Impact factor: 3.270

Review 4. Homers regulate drug-induced neuroplasticity: implications for addiction.

Authors: Karen K Szumlinski; Alexis W Ary; Kevin D Lominac
Journal: Biochem Pharmacol Date: 2007-07-27 Impact factor: 5.858

5. Heightened drug-seeking motivation following extended daily access to self-administered cocaine.

Authors: Osnat Ben-Shahar; Eric J Posthumus; Stephanie A Waldroup; Aaron Ettenberg
Journal: Prog Neuropsychopharmacol Biol Psychiatry Date: 2008-01-11 Impact factor: 5.067

6. CaMKII: a biochemical bridge linking accumbens dopamine and glutamate systems in cocaine seeking.

Authors: Sharon M Anderson; Katie R Famous; Ghazaleh Sadri-Vakili; Vidhya Kumaresan; Heath D Schmidt; Caroline E Bass; Ernest F Terwilliger; Jang-Ho J Cha; R Christopher Pierce
Journal: Nat Neurosci Date: 2008-02-17 Impact factor: 24.884

7. Cell surface AMPA receptors in the rat nucleus accumbens increase during cocaine withdrawal but internalize after cocaine challenge in association with altered activation of mitogen-activated protein kinases.

Authors: Amy C Boudreau; Jeremy M Reimers; Michael Milovanovic; Marina E Wolf
Journal: J Neurosci Date: 2007-09-26 Impact factor: 6.167

8. Repeated N-acetylcysteine administration alters plasticity-dependent effects of cocaine.

Authors: Aric Madayag; Doug Lobner; Kristen S Kau; John R Mantsch; Omer Abdulhameed; Matthew Hearing; Mark D Grier; David A Baker
Journal: J Neurosci Date: 2007-12-19 Impact factor: 6.167

9. Glutamate and aspartate levels in the nucleus accumbens during cocaine self-administration and extinction: a time course microdialysis study.

Authors: M Miguéns; N Del Olmo; A Higuera-Matas; I Torres; C García-Lecumberri; E Ambrosio
Journal: Psychopharmacology (Berl) Date: 2007-10-17 Impact factor: 4.530

10. Formation of accumbens GluR2-lacking AMPA receptors mediates incubation of cocaine craving.

Authors: Kelly L Conrad; Kuei Y Tseng; Jamie L Uejima; Jeremy M Reimers; Li-Jun Heng; Yavin Shaham; Michela Marinelli; Marina E Wolf
Journal: Nature Date: 2008-05-25 Impact factor: 49.962

118 in total

1. Dopamine-regulated microRNA MiR-181a controls GluA2 surface expression in hippocampal neurons.

Authors: Reuben Saba; Peter H Störchel; Ayla Aksoy-Aksel; Frauke Kepura; Giordano Lippi; Tim D Plant; Gerhard M Schratt
Journal: Mol Cell Biol Date: 2011-12-05 Impact factor: 4.272

2. Alterations in AMPA receptor subunits and TARPs in the rat nucleus accumbens related to the formation of Ca²⁺-permeable AMPA receptors during the incubation of cocaine craving.

Authors: Carrie R Ferrario; Jessica A Loweth; Mike Milovanovic; Kerstin A Ford; Gregorio L Galiñanes; Li-Jun Heng; Kuei Y Tseng; Marina E Wolf
Journal: Neuropharmacology Date: 2011-01-27 Impact factor: 5.250

Review 3. New medications for drug addiction hiding in glutamatergic neuroplasticity.

Authors: P W Kalivas; N D Volkow
Journal: Mol Psychiatry Date: 2011-04-26 Impact factor: 15.992

4. Getting to the core of addiction: hatching the addiction egg.

Authors: Peter W Kalivas; Kathleen Brady
Journal: Nat Med Date: 2012-04-05 Impact factor: 53.440

5. Temporally dependent changes in cocaine-induced synaptic plasticity in the nucleus accumbens shell are reversed by D1-like dopamine receptor stimulation.

Authors: Pavel I Ortinski; Fair M Vassoler; Gregory C Carlson; R Christopher Pierce
Journal: Neuropsychopharmacology Date: 2012-03-14 Impact factor: 7.853

6. Cav1.2 L-type Ca²⁺ channels mediate cocaine-induced GluA1 trafficking in the nucleus accumbens, a long-term adaptation dependent on ventral tegmental area Ca(v)1.3 channels.

Authors: Kathryn Schierberl; Jin Hao; Thomas F Tropea; Stephen Ra; Thomas P Giordano; Qinghao Xu; Sandra M Garraway; Franz Hofmann; Sven Moosmang; Joerg Striessnig; Charles E Inturrisi; Anjali M Rajadhyaksha
Journal: J Neurosci Date: 2011-09-21 Impact factor: 6.167