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Literature DB >> 20655530

Endometrial expression of relaxin and relaxin receptor in endometriosis.

Sara S Morelli¹, Felice Petraglia, Gerson Weiss, Stefano Luisi, Pasquale Florio, Andrea Wojtczuk, Laura T Goldsmith.

Abstract

Our studies demonstrate significantly lower expression of relaxin and its receptor in ectopic endometriotic tissues than their expression in eutopic endometrium and in endometrium from normal controls. These data suggest that in normal and eutopic endometrium, relaxin may exert a protective effect against endometriosis.

Entities: Chemical Disease Gene Species

Mesh：

Substances：

Year: 2010 PMID： 20655530 PMCID： PMC2988985 DOI： 10.1016/j.fertnstert.2010.06.051

Source DB: PubMed Journal: Fertil Steril ISSN： 0015-0282 Impact factor: 7.329

16 in total

1. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method.

Authors: K J Livak; T D Schmittgen
Journal: Methods Date: 2001-12 Impact factor: 3.608

2. Developmental regulation of the human relaxin genes in the decidua and placenta: overexpression in the preterm premature rupture of the fetal membranes.

Authors: L V Bogic; S Y Yamamoto; L K Millar; G D Bryant-Greenwood
Journal: Biol Reprod Date: 1997-10 Impact factor: 4.285

Review 3. The epidemiology of endometriosis.

Authors: M B Goldman; D W Cramer
Journal: Prog Clin Biol Res Date: 1990

4. Relaxin regulates endometrial structure and function in the rhesus monkey.

Authors: Laura T Goldsmith; Gerson Weiss
Journal: Ann N Y Acad Sci Date: 2005-05 Impact factor: 5.691

5. The human relaxin receptor (LGR7): expression in the fetal membranes and placenta.

Authors: K Lowndes; A Amano; S Y Yamamoto; G D Bryant-Greenwood
Journal: Placenta Date: 2005-09-12 Impact factor: 3.481

6. Relaxin gene and protein expression and its regulation of procollagenase and vascular endothelial growth factor in human endometrial cells.

Authors: Smita Palejwala; Linda Tseng; Andrea Wojtczuk; Gerson Weiss; Laura T Goldsmith
Journal: Biol Reprod Date: 2002-06 Impact factor: 4.285

7. Interleukin 1alpha and tissue-lytic matrix metalloproteinase-1 are elevated in ectopic endometrium of patients with endometriosis.

Authors: G Hudelist; H Lass; J Keckstein; I Walter; F Wieser; R Wenzl; R Mueller; K Czerwenka; E Kubista; C F Singer
Journal: Hum Reprod Date: 2005-03-03 Impact factor: 6.918

Endometrial expression of relaxin and relaxin receptor in endometriosis.

1. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method.

2. Developmental regulation of the human relaxin genes in the decidua and placenta: overexpression in the preterm premature rupture of the fetal membranes.

Review 3. The epidemiology of endometriosis.

4. Relaxin regulates endometrial structure and function in the rhesus monkey.

5. The human relaxin receptor (LGR7): expression in the fetal membranes and placenta.

6. Relaxin gene and protein expression and its regulation of procollagenase and vascular endothelial growth factor in human endometrial cells.

7. Interleukin 1alpha and tissue-lytic matrix metalloproteinase-1 are elevated in ectopic endometrium of patients with endometriosis.

8. Transvaginal ultrasonography in women receiving emergency contraception.

9. Relaxin regulation of endometrial structure and function in the rhesus monkey.

Review 10. Matrix metalloproteinases and endometriosis.

Review 1. Endometrial biomarkers for the non-invasive diagnosis of endometriosis.

2. Relationship of relaxin hormone and thumb carpometacarpal joint arthritis.