Literature DB >> 20655214

Design and synthesis of HCV agents with sequential triple inhibitory potentials.

Tianmin Zhu1, Mahdi B Fawzi, Michael Flint, Fangming Kong, Jan Szeliga, Russ Tsao, Anita Y M Howe, Weitao Pan.   

Abstract

The union of HCV-796, a potent selective HCV NS5B polymerase inhibitor, and Ribavirin, a molecule with activities against a wide spectrum of viruses, resulted in a class of new anti-HCV agents with a sequential triple inhibitory mechanism. Copyright 2010 Elsevier Ltd. All rights reserved.

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Year:  2010        PMID: 20655214     DOI: 10.1016/j.bmcl.2010.06.156

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN: 0960-894X            Impact factor:   2.823


  1 in total

1.  Thermodynamic modelling of solubility and preferential solvation for ribavirin (II) in co-solvent mixtures of (methanol, n-propanol, acetonitrile or 1,4-dioxane) + water.

Authors:  Xinbao Li; Yang Cong; Wentian Li; Pengyao Yan; Hongkun Zhao
Journal:  J Chem Thermodyn       Date:  2017-07-24       Impact factor: 3.178

  1 in total

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