Literature DB >> 20654246

[Treatment of infantile parotid hemangioma with propranolol].

Xue-jian Liu1, Zhong-ping Qin, Mao-zhong Tai, Ke-lei Li, Chun-xiao Ge.   

Abstract

OBJECTIVE: To evaluate the short-term results and safety of propranolol for the treatment of infantile parotid hemangioma.
METHODS: Oral propranolol was administered to 17 infants with parotid hemangioma at a dose of 1.0-1.5 mg per kilogram of body weight per day. The patients were revisited once a week. The changes of the tumor size, texture and colour were monitored and recorded at a regular interval. The adverse effects after medication were observed and managed accordingly. The short-term results were evaluated using a 4 scales system.
RESULTS: Among the 17 patients treated, the follow-up time was 5 to 10 months. The overall response was scale I in 0 patient, scale II in 0 patients, scale III in 5 patients, and scale IV in 12 patients. No serious adverse effects were encountered.
CONCLUSIONS: Oral propranolol at a lower dose is a safe and effective method for the treatment of infantile parotid hemangioma. The short-term results were excellent and the side effects minimal.

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Year:  2010        PMID: 20654246

Source DB:  PubMed          Journal:  Zhonghua Kou Qiang Yi Xue Za Zhi        ISSN: 1002-0098


  1 in total

1.  Propranolol intervention therapy for infants with facial hemangioma.

Authors:  Jian Meng; Zhiping Li; Qianping Gu; Jie Zhang; Qianwei Zhuang; Yameng Si; Aixia Zhang
Journal:  Contemp Oncol (Pozn)       Date:  2012-11-20
  1 in total

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