OBJECTIVE: To observe the clinical therapeutic effect of the method of clearing away heat, expelling dampness, promoting blood circulation and healing ulcer on ulcerative colitis. METHODS: The 100 cases were randomly divided into a control group of 45 cases treated withretention enema of the enterosoluble tablet sulfasalazine once every evening and a treatment group of 55 cases treated with retention enema of the decoction for clearing away heat, expelling dampness, promoting blood circulation and healing ulcer once every evening. The patients in both groups orally took Chinese drug for basic treatment for 30 days as a course. After treatment, the clinical therapeutic effects in the 2 groups were compared and changed symptoms in intestinal mucosa were observed under endoscope. RESULTS: The total effective rate of treatment group was better in relieving symptoms of TCM syndrome (90.9%) and intestinal mucosa (83.3%) than that of control group (68.9%, 56.3%) (P<0.01 or P<0.05). CONCLUSION: With good therapeutic effect on ulcerative colitis, Qinghua Huoxue Lianyang therapy (clearing away heat, expelling dampness, promoting blood circulation and healing ulcer) can obviously repair intestinal mucosa.
RCT Entities:
OBJECTIVE: To observe the clinical therapeutic effect of the method of clearing away heat, expelling dampness, promoting blood circulation and healing ulcer on ulcerative colitis. METHODS: The 100 cases were randomly divided into a control group of 45 cases treated with retention enema of the enterosoluble tablet sulfasalazine once every evening and a treatment group of 55 cases treated with retention enema of the decoction for clearing away heat, expelling dampness, promoting blood circulation and healing ulcer once every evening. The patients in both groups orally took Chinese drug for basic treatment for 30 days as a course. After treatment, the clinical therapeutic effects in the 2 groups were compared and changed symptoms in intestinal mucosa were observed under endoscope. RESULTS: The total effective rate of treatment group was better in relieving symptoms of TCM syndrome (90.9%) and intestinal mucosa (83.3%) than that of control group (68.9%, 56.3%) (P<0.01 or P<0.05). CONCLUSION: With good therapeutic effect on ulcerative colitis, Qinghua Huoxue Lianyang therapy (clearing away heat, expelling dampness, promoting blood circulation and healing ulcer) can obviously repair intestinal mucosa.