Literature DB >> 20652300

Current issues in antiplatelet therapy for stroke prevention: the importance of stroke subtypes and differences between stroke and MI patients.

H S Kirshner1.   

Abstract

Ischaemic stroke, the most common type of stroke, is classified into three main subtypes: large-vessel disease, lacunar or small-vessel disease, and cardioembolic; two further subtypes include a determined aetiology of "other" and cryptogenic. Although a substantial amount of literature exists concerning current guidelines for the secondary prevention of ischaemic stroke, treatment strategies for stroke subtypes as well as the reasons why these subtypes are significant have yet to be clearly defined. Furthermore, treatment strategies for secondary prevention of ischaemic stroke differ between patients who have suffered a previous stroke and those who have suffered a myocardial infarction. Antiplatelet therapies offer treatment that is as efficacious as warfarin, but with less severe bleeding. This review examines the importance of the different subtypes of stroke as well as differentiating between treating a heart patient and a stroke patient for secondary stroke prevention, including the advantages of using antiplatelet therapy over anticoagulants.

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Year:  2010        PMID: 20652300     DOI: 10.1007/s00415-010-5667-4

Source DB:  PubMed          Journal:  J Neurol        ISSN: 0340-5354            Impact factor:   4.849


  65 in total

1.  Secondary stroke prevention with ximelagatran versus warfarin in patients with atrial fibrillation: pooled analysis of SPORTIF III and V clinical trials.

Authors:  Paul T Akins; Harvey A Feldman; Robert G Zoble; David Newman; Stefan G Spitzer; Hans-Christoph Diener; Gregory W Albers
Journal:  Stroke       Date:  2007-01-25       Impact factor: 7.914

2.  Risk factors for ischemic stroke subtypes: the Atherosclerosis Risk in Communities study.

Authors:  Tetsuya Ohira; Eyal Shahar; Lloyd E Chambless; Wayne D Rosamond; Thomas H Mosley; Aaron R Folsom
Journal:  Stroke       Date:  2006-08-24       Impact factor: 7.914

3.  Aspirin inhibits p44/42 mitogen-activated protein kinase and is protective against hypoxia/reoxygenation neuronal damage.

Authors:  Nina Vartiainen; Gundars Goldsteins; Velta Keksa-Goldsteine; Pak H Chan; Jari Koistinaho
Journal:  Stroke       Date:  2003-02-27       Impact factor: 7.914

4.  Fruit and vegetable consumption and risk of stroke: a meta-analysis of cohort studies.

Authors:  Luc Dauchet; Philippe Amouyel; Jean Dallongeville
Journal:  Neurology       Date:  2005-10-25       Impact factor: 9.910

5.  A randomised, blinded, trial of clopidogrel versus aspirin in patients at risk of ischaemic events (CAPRIE). CAPRIE Steering Committee.

Authors: 
Journal:  Lancet       Date:  1996-11-16       Impact factor: 79.321

6.  Association of serum lipid indices with large artery atherosclerotic stroke.

Authors:  O Y Bang; J L Saver; D S Liebeskind; S Pineda; B Ovbiagele
Journal:  Neurology       Date:  2007-12-26       Impact factor: 9.910

7.  Abdominal obesity and risk of ischemic stroke: the Northern Manhattan Stroke Study.

Authors:  Seung-Han Suk; Ralph L Sacco; Bernadette Boden-Albala; Jian F Cheun; John G Pittman; Mitchell S Elkind; Myunghee C Paik
Journal:  Stroke       Date:  2003-05-29       Impact factor: 7.914

8.  Fish consumption and risk of stroke in men.

Authors:  Ka He; Eric B Rimm; Anwar Merchant; Bernard A Rosner; Meir J Stampfer; Walter C Willett; Alberto Ascherio
Journal:  JAMA       Date:  2002-12-25       Impact factor: 56.272

Review 9.  Classification of stroke subtypes.

Authors:  P Amarenco; J Bogousslavsky; L R Caplan; G A Donnan; M G Hennerici
Journal:  Cerebrovasc Dis       Date:  2009-04-03       Impact factor: 2.762

10.  Classification of subtype of acute ischemic stroke. Definitions for use in a multicenter clinical trial. TOAST. Trial of Org 10172 in Acute Stroke Treatment.

Authors:  H P Adams; B H Bendixen; L J Kappelle; J Biller; B B Love; D L Gordon; E E Marsh
Journal:  Stroke       Date:  1993-01       Impact factor: 7.914

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  2 in total

1.  Basilar branch occlusion.

Authors:  Jaime Gállego Culleré; María Elena Erro Aguirre
Journal:  Curr Treat Options Cardiovasc Med       Date:  2011-06

2.  Discovery of prognostic biomarker candidates of lacunar infarction by quantitative proteomics of microvesicles enriched plasma.

Authors:  Arnab Datta; Christopher P Chen; Siu Kwan Sze
Journal:  PLoS One       Date:  2014-04-21       Impact factor: 3.240

  2 in total

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