Literature DB >> 20652214

[Hemiparesis in acute lymphoblastic leukemia].

M Karremann1, G von Komorowski, E Neumaier-Probst, M Dürken.   

Abstract

The case of an adolescent female patient with acute lymphoblastic leukemia and stroke-like hemiparesis demonstrates a typical manifestation of methotrexate-induced acute encephalopathy. This rare entity occurs both in children and adults and can result from intrathecal as well as high dose intravenous administration of methotrexate. Diagnosis can confidently be made using cerebral MRI including diffusion-weighted imaging (DWI), so that patients can be informed about the favorable prognosis.

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Year:  2010        PMID: 20652214     DOI: 10.1007/s00117-010-2042-5

Source DB:  PubMed          Journal:  Radiologe        ISSN: 0033-832X            Impact factor:   0.635


  5 in total

1.  Reversible acute methotrexate leukoencephalopathy: atypical brain MR imaging features.

Authors:  France Ziereisen; Bernard Dan; Nadira Azzi; Alina Ferster; Nash Damry; Catherine Christophe
Journal:  Pediatr Radiol       Date:  2005-12-21

2.  Age and high-dose methotrexate are associated to clinical acute encephalopathy in FRALLE 93 trial for acute lymphoblastic leukemia in children.

Authors:  M N Dufourg; J Landman-Parker; M F Auclerc; C Schmitt; Y Perel; G Michel; P Levy; G Couillault; V Gandemer; M D Tabone; F Demeocq; J P Vannier; T Leblanc; G Leverger; A Baruchel
Journal:  Leukemia       Date:  2006-12-14       Impact factor: 11.528

3.  Acute methotrexate neurotoxicity: findings on diffusion-weighted imaging and correlation with clinical outcome.

Authors:  Nancy Rollins; Naomi Winick; Robert Bash; Timothy Booth
Journal:  AJNR Am J Neuroradiol       Date:  2004 Nov-Dec       Impact factor: 3.825

4.  Clinical and radiological characteristics of methotrexate-induced acute encephalopathy in pediatric patients with cancer.

Authors:  H Inaba; R B Khan; F H Laningham; K R Crews; C-H Pui; N C Daw
Journal:  Ann Oncol       Date:  2007-10-17       Impact factor: 32.976

5.  Diffusion and perfusion imaging in subacute neurotoxicity following high-dose intravenous methotrexate.

Authors:  April F Eichler; Tracy T Batchelor; John W Henson
Journal:  Neuro Oncol       Date:  2007-05-23       Impact factor: 12.300

  5 in total

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