Literature DB >> 20651677

Obesity: New life for antidiabetic drugs.

Riekelt H Houtkooper, Johan Auwerx.   

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Year:  2010        PMID： 20651677      PMCID： PMC3852809          DOI： 10.1038/466443a

Source DB:  PubMed          Journal:  Nature        ISSN： 0028-0836            Impact factor:   49.962


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  15 in total

1.  Cyclin-dependent kinase 5 promotes insulin exocytosis.

Authors:  L Lilja; S N Yang; D L Webb; L Juntti-Berggren; P O Berggren; C Bark
Journal:  J Biol Chem       Date:  2001-07-06       Impact factor: 5.157

2.  Nuclear receptor corepressor RIP140 regulates fat accumulation.

Authors:  Göran Leonardsson; Jenny H Steel; Mark Christian; Victoria Pocock; Stuart Milligan; Jimmy Bell; Po-Wah So; Gema Medina-Gomez; Antonio Vidal-Puig; Roger White; Malcolm G Parker
Journal:  Proc Natl Acad Sci U S A       Date:  2004-05-20       Impact factor: 11.205

3.  Cdk5-dependent regulation of glucose-stimulated insulin secretion.

Authors:  Fan-Yan Wei; Kazuaki Nagashima; Toshio Ohshima; Yasunori Saheki; Yun-Fei Lu; Masayuki Matsushita; Yuichiro Yamada; Katsuhiko Mikoshiba; Yutaka Seino; Hideki Matsui; Kazuhito Tomizawa
Journal:  Nat Med       Date:  2005-09-11       Impact factor: 53.440

4.  A cold-inducible coactivator of nuclear receptors linked to adaptive thermogenesis.

Authors:  P Puigserver; Z Wu; C W Park; R Graves; M Wright; B M Spiegelman
Journal:  Cell       Date:  1998-03-20       Impact factor: 41.582

Review 5.  Peroxisome proliferator-activated receptor-gamma calls for activation in moderation: lessons from genetics and pharmacology.

Authors:  Chris Knouff; Johan Auwerx
Journal:  Endocr Rev       Date:  2004-12       Impact factor: 19.871

Review 6.  A decade of CDK5.

Authors:  R Dhavan; L H Tsai
Journal:  Nat Rev Mol Cell Biol       Date:  2001-10       Impact factor: 94.444

Review 7.  Anti-inflammatory actions of PPAR ligands: new insights on cellular and molecular mechanisms.

Authors:  Daniel S Straus; Christopher K Glass
Journal:  Trends Immunol       Date:  2007-11-05       Impact factor: 16.687

8.  Nucleoprotein complexes that regulate gene expression in adipocyte differentiation: direct participation of c-fos.

Authors:  R J Distel; H S Ro; B S Rosen; D L Groves; B M Spiegelman
Journal:  Cell       Date:  1987-06-19       Impact factor: 41.582

9.  A Pro12Ala substitution in PPARgamma2 associated with decreased receptor activity, lower body mass index and improved insulin sensitivity.

Authors:  S S Deeb; L Fajas; M Nemoto; J Pihlajamäki; L Mykkänen; J Kuusisto; M Laakso; W Fujimoto; J Auwerx
Journal:  Nat Genet       Date:  1998-11       Impact factor: 38.330

10.  Effect of rosiglitazone on the risk of myocardial infarction and death from cardiovascular causes.

Authors:  Steven E Nissen; Kathy Wolski
Journal:  N Engl J Med       Date:  2007-05-21       Impact factor: 91.245
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  14 in total

1.  Hepatocyte nuclear factor 1b is a novel negative regulator of white adipocyte differentiation.

Authors:  Xin Wang; Hao Wu; Weihua Yu; Jiangzheng Liu; Jie Peng; Nai Liao; Jieling Zhang; Xiaodi Zhang; Chunxu Hai
Journal:  Cell Death Differ       Date:  2017-06-16       Impact factor: 15.828

2.  Ligand and receptor dynamics contribute to the mechanism of graded PPARγ agonism.

Authors:  Travis S Hughes; Michael J Chalmers; Scott Novick; Dana S Kuruvilla; Mi Ra Chang; Theodore M Kamenecka; Mark Rance; Bruce A Johnson; Thomas P Burris; Patrick R Griffin; Douglas J Kojetin
Journal:  Structure       Date:  2012-01-11       Impact factor: 5.006

3.  Peroxisome proliferator-activated receptor-γ regulates inflammation and renin-angiotensin system activity in the hypothalamic paraventricular nucleus and ameliorates peripheral manifestations of heart failure.

Authors:  Yang Yu; Zhi-Hua Zhang; Shun-Guang Wei; Robert M Weiss; Robert B Felder
Journal:  Hypertension       Date:  2011-11-14       Impact factor: 10.190

4.  Structural insights for the design of new PPARgamma partial agonists with high binding affinity and low transactivation activity.

Authors:  Laura Guasch; Esther Sala; Cristina Valls; Mayte Blay; Miquel Mulero; Lluís Arola; Gerard Pujadas; Santiago Garcia-Vallvé
Journal:  J Comput Aided Mol Des       Date:  2011-06-21       Impact factor: 3.686

5.  Thiazolidinedione-dependent activation of sphingosine kinase 1 causes an anti-fibrotic effect in renal mesangial cells.

Authors:  A Koch; A Völzke; C Wünsche; D Meyer zu Heringdorf; A Huwiler; J Pfeilschifter
Journal:  Br J Pharmacol       Date:  2012-06       Impact factor: 8.739

6.  Comparative Evaluation of Chiglitazar and Sitagliptin on the Levels of Retinol-Binding Protein 4 and Its Correlation With Insulin Resistance in Patients With Type 2 Diabetes.

Authors:  Yunting Zhou; Huiying Wang; Yuming Wang; Xiaohua Xu; Fengfei Li; Junming Zhou; Ting Shan; Rong Huang; Tingting Cai; Xiaomei Liu; Xiaofei Su; Huiqin Li; Jianhua Ma
Journal:  Front Endocrinol (Lausanne)       Date:  2022-04-25       Impact factor: 6.055

7.  Impact of GNB3-C825T, ADRB3-Trp64Arg, UCP2-3'UTR 45 bp del/ins, and PPARγ-Pro12Ala polymorphisms on Bofutsushosan response in obese subjects: a randomized, double-blind, placebo-controlled trial.

Authors:  Junghyun Park; Shambhunath Bose; Sun-Woo Hong; Dong-Ki Lee; Jae-Wook Yoo; Chi-Yeon Lim; Myeongjong Lee; Hojun Kim
Journal:  J Med Food       Date:  2014-05       Impact factor: 2.786

8.  Identification of the antibiotic ionomycin as an unexpected peroxisome proliferator-activated receptor γ (PPARγ) ligand with a unique binding mode and effective glucose-lowering activity in a mouse model of diabetes.

Authors:  W Zheng; X Feng; L Qiu; Z Pan; R Wang; S Lin; D Hou; L Jin; Y Li
Journal:  Diabetologia       Date:  2012-11-23       Impact factor: 10.122

9.  In Vitro and In Vivo Characterizations of Chiglitazar, a Newly Identified PPAR Pan-Agonist.

Authors:  B K He; Z Q Ning; Z B Li; S Shan; D S Pan; B C B Ko; P P Li; Z F Shen; G F Dou; B L Zhang; X P Lu; Y Gao
Journal:  PPAR Res       Date:  2012-10-22       Impact factor: 4.964

10.  Central obesity in males affected by a dyslipidemia-associated genetic polymorphism on APOA1/C3/A4/A5 gene cluster.

Authors:  M-C Hsu; C-S Chang; K-T Lee; H-Y Sun; Y-S Tsai; P-H Kuo; K-C Young; C-H Wu
Journal:  Nutr Diabetes       Date:  2013-03-04       Impact factor: 5.097
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