Literature DB >> 20651270

Gender differences in treatment of severe carotid stenosis after transient ischemic attack.

Sharon N Poisson1, S Claiborne Johnston, Stephen Sidney, Jeffrey G Klingman, Mai N Nguyen-Huynh.   

Abstract

BACKGROUND AND
PURPOSE: Gender differences in carotid endarterectomy (CEA) rates after transient ischemic attack are not well studied, although some reports suggest that eligible men are more likely to have CEA than women after stroke.
METHODS: We retrospectively identified all patients diagnosed with transient ischemic attack and >or=70% carotid stenosis on ultrasound in 2003 to 2004 from 19 emergency departments. Medical records were abstracted for clinical data; 90-day follow-up events, including stroke, cardiovascular events, or death; CEA within 6 months; and postoperative 30-day outcomes. We assessed gender as a predictor of CEA and its complications adjusting for demographic and clinical variables as well as time to CEA between groups.
RESULTS: Of 299 patients identified, 47% were women. Women were older with higher presenting systolic blood pressure and less likely to smoke or to have coronary artery disease or diabetes. Fewer women (36.4%) had CEA than men (53.8%; P=0.004). Reasons for withholding surgical treatment were similar in women and men, and there were no differences in follow-up stroke, cardiovascular event, postoperative complications, or death. Time to CEA was also significantly delayed in women.
CONCLUSIONS: Women with severe carotid stenosis and recent transient ischemic attack are less likely to undergo CEA than men, and surgeries are more delayed.

Entities:  

Mesh:

Year:  2010        PMID: 20651270      PMCID: PMC2946224          DOI: 10.1161/STROKEAHA.110.580977

Source DB:  PubMed          Journal:  Stroke        ISSN: 0039-2499            Impact factor:   7.914


  36 in total

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4.  Short-term prognosis after emergency department diagnosis of TIA.

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Review 9.  Sex differences in carotid endarterectomy outcomes: results from the Ontario Carotid Endarterectomy Registry.

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  14 in total

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Authors:  Paola De Rango; Martin M Brown; Didier Leys; Leys Didier; Virginia J Howard; Wesley S Moore; Maurizio Paciaroni; Peter Ringleb; Caron Rockman; Valeria Caso
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2.  Peripheral arterial disease in women: the effect of gender on diagnosis and treatment.

Authors:  Eduardo A Hernandez-Vila
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Review 3.  Carotid Artery Stenosis in Women.

Authors:  Michael J McArdle; Anne L Abbott; Zvonimir Krajcer
Journal:  Tex Heart Inst J       Date:  2018-08-01

Review 4.  Importance of sex and gender in ischaemic stroke and carotid atherosclerotic disease.

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5.  Carotid endarterectomy national trends over a decade: does sex matter?

Authors:  Sreyram Kuy; Anahita Dua; Sapan S Desai; Peter J Rossi; Gary R Seabrook; Brian D Lewis; Bhavin Patel; Sreyreath Kuy; Cheong J Lee; Rishi Subbarayan; Kellie R Brown
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6.  Stroke prevention in women: synopsis of the 2014 American Heart Association/American Stroke Association guideline.

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8.  Reduction in early stroke risk in carotid stenosis with transient ischemic attack associated with statin treatment.

Authors:  Áine Merwick; Gregory W Albers; Ethem M Arsava; Hakan Ay; David Calvet; Shelagh B Coutts; Brett L Cucchiara; Andrew M Demchuk; Matthew F Giles; Jean-Louis Mas; Jean Marc Olivot; Francisco Purroy; Peter M Rothwell; Jeffrey L Saver; Vijay K Sharma; Georgios Tsivgoulis; Peter J Kelly
Journal:  Stroke       Date:  2013-08-01       Impact factor: 7.914

9.  In-hospital and one-year outcomes are similar for women and men following transcarotid artery revascularization in symptomatic and asymptomatic patients.

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10.  Meta- analysis and meta-regression analysis of the associations between sex and the operative outcomes of carotid endarterectomy.

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