OBJECTIVE: The objective of our study was to illustrate how the properties of hepatocyte-specific MR contrast agents can be used in the dynamic evaluation of the biliary system. CONCLUSION: Because of their dual route of excretion through the kidneys and the liver, gadolinium-based, hepatocyte-specific MR contrast agents can be used to evaluate the biliary tract as an off-label use. Images are obtained during the hepatocyte phase, which usually occurs within 20-40 minutes after injection depending on the specific contrast agent selected. Potential uses include showing variant biliary anatomy and choledocholithiasis. Evaluation for acute cholecystitis is possible by assessing for reflux of contrast material across the cystic duct. Additionally, these agents have value in both presurgical and postsurgical imaging for showing anatomy and complications. Finally, these agents are useful in the evaluation of choledochal cysts.
OBJECTIVE: The objective of our study was to illustrate how the properties of hepatocyte-specific MR contrast agents can be used in the dynamic evaluation of the biliary system. CONCLUSION: Because of their dual route of excretion through the kidneys and the liver, gadolinium-based, hepatocyte-specific MR contrast agents can be used to evaluate the biliary tract as an off-label use. Images are obtained during the hepatocyte phase, which usually occurs within 20-40 minutes after injection depending on the specific contrast agent selected. Potential uses include showing variant biliary anatomy and choledocholithiasis. Evaluation for acute cholecystitis is possible by assessing for reflux of contrast material across the cystic duct. Additionally, these agents have value in both presurgical and postsurgical imaging for showing anatomy and complications. Finally, these agents are useful in the evaluation of choledochal cysts.
Authors: Scott K Nagle; Reed F Busse; Anja C Brau; Jean H Brittain; Alex Frydrychowicz; Yuji Iwadate; Scott B Reeder Journal: J Magn Reson Imaging Date: 2012-05-30 Impact factor: 4.813
Authors: Shilpa Reddy; Camila Lopes Vendrami; Pardeep Mittal; Amir A Borhani; Courtney C Moreno; Frank H Miller Journal: Abdom Radiol (NY) Date: 2021-02-12
Authors: Jesse L Courtier; Emily R Perito; Sue Rhee; Patrika Tsai; Melvin B Heyman; John D MacKenzie Journal: J Pediatr Gastroenterol Nutr Date: 2012-04 Impact factor: 2.839
Authors: Luciana Carmen Zattar-Ramos; Regis Otaviano Franca Bezerra; Luis Tenório de Brito Siqueira; Marcos Roberto Menezes; Claudia da Costa Leite; Giovanni Guido Cerri Journal: Radiol Bras Date: 2017 Nov-Dec