Literature DB >> 2065119

Animal models for the study of alcoholism: utility of selected lines.

J C Froehlich1, T K Li.   

Abstract

One recent advance in the field of alcohol research has been the recognition that a predisposition to develop alcoholism is, in part, genetically determined. It now remains to identify the factors, which, when inherited, increase risk for alcoholism. One approach to this problem is to analyze how organisms with identifiable genetic predisposition towards ethanol drinking differ from organisms without genetic risk. Such an approach may lead to the identification of neurochemical, neurophysiological or neuroanatomical factors which, when inherited alone, or in combination, serve to predispose an organism towards ethanol drinking.

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Year:  1991        PMID: 2065119     DOI: 10.1300/J069v10n01_05

Source DB:  PubMed          Journal:  J Addict Dis        ISSN: 1055-0887


  13 in total

1.  Combining naltrexone and prazosin in a single oral medication decreases alcohol drinking more effectively than does either drug alone.

Authors:  Janice C Froehlich; Brett J Hausauer; Dennis D Rasmussen
Journal:  Alcohol Clin Exp Res       Date:  2013-07-22       Impact factor: 3.455

2.  Nicotine infusion in the wake-promoting basal forebrain enhances alcohol-induced activation of nucleus accumbens.

Authors:  Rishi Sharma; Samuel Dumontier; David DeRoode; Pradeep Sahota; Mahesh M Thakkar
Journal:  Alcohol Clin Exp Res       Date:  2014-10-21       Impact factor: 3.455

3.  Prazosin Reduces Alcohol Intake in an Animal Model of Alcohol Relapse.

Authors:  Janice C Froehlich; Brett Hausauer; Stephen Fischer; Bradley Wise; Dennis D Rasmussen
Journal:  Alcohol Clin Exp Res       Date:  2015-08       Impact factor: 3.455

4.  Varenicline Reduces Alcohol Intake During Repeated Cycles of Alcohol Reaccess Following Deprivation in Alcohol-Preferring (P) Rats.

Authors:  Janice C Froehlich; Emily R Nicholson; Julian E Dilley; Nick J Filosa; Logan C Rademacher; Teal N Smith
Journal:  Alcohol Clin Exp Res       Date:  2017-07-10       Impact factor: 3.455

5.  Combining Varenicline (Chantix) with Naltrexone Decreases Alcohol Drinking More Effectively Than Does Either Drug Alone in a Rodent Model of Alcoholism.

Authors:  Janice C Froehlich; Stephen M Fischer; Julian E Dilley; Emily R Nicholson; Teal N Smith; Nick J Filosa; Logan C Rademacher
Journal:  Alcohol Clin Exp Res       Date:  2016-07-29       Impact factor: 3.455

6.  Differential expression of guanosine triphosphate binding proteins in men at high and low risk for the future development of alcoholism.

Authors:  G S Wand; C Waltman; C S Martin; M E McCaul; M A Levine; D Wolfgang
Journal:  J Clin Invest       Date:  1994-09       Impact factor: 14.808

7.  Co-Administration of Low-Dose Naltrexone and Bupropion Reduces Alcohol Drinking in Alcohol-Preferring (P) Rats.

Authors:  Emily R Nicholson; Julian E Dilley; Janice C Froehlich
Journal:  Alcohol Clin Exp Res       Date:  2018-01-22       Impact factor: 3.455

8.  Differences in the hypothermic response to ethanol in rats selectively bred for oral ethanol preference and nonpreference.

Authors:  R B Stewart; D L Kurtz; M Zweifel; T K Li; J C Froehlich
Journal:  Psychopharmacology (Berl)       Date:  1992       Impact factor: 4.530

9.  The alpha1-adrenergic receptor antagonist, prazosin, reduces alcohol drinking in alcohol-preferring (P) rats.

Authors:  Dennis D Rasmussen; Laura L Alexander; Murray A Raskind; Janice C Froehlich
Journal:  Alcohol Clin Exp Res       Date:  2008-11-19       Impact factor: 3.455

Review 10.  Genetics of alcoholism: role of the endogenous opioid system.

Authors:  C Gianoulakis; J P de Waele
Journal:  Metab Brain Dis       Date:  1994-06       Impact factor: 3.584

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