Literature DB >> 2064936

Interleukin-1 beta stimulates fibroblast elastase activity.

F Croute1, E Delaporte, J Y Bonnefoy, C Fertin, J Thivolet, J F Nicolas.   

Abstract

We report the stimulation of elastase activity of human skin fibroblasts by interleukin-1 beta (IL-1). Elastase activity was determined by the hydrolysis of the synthetic substrate succinoyl trialanine paranitroanilide (Suc(Ala3)NA). Recombinant human IL-1 beta induced a concentration-dependent increase in the elastase activity of fibroblasts. The supernatants of keratinocyte cultures that contained IL-1/ETAF showed similar stimulatory activity.

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Year:  1991        PMID： 2064936     DOI： 10.1111/j.1365-2133.1991.tb04946.x

Source DB:  PubMed          Journal:  Br J Dermatol        ISSN： 0007-0963            Impact factor:   9.302


  7 in total

Review 1.  A cytokine axis regulates elastin formation and degradation.

Authors:  Erin P Sproul; W Scott Argraves
Journal:  Matrix Biol       Date:  2012-11-13       Impact factor: 11.583

2.  Elafin, a serine elastase inhibitor, attenuates post-cardiac transplant coronary arteriopathy and reduces myocardial necrosis in rabbits afer heterotopic cardiac transplantation.

Authors:  B Cowan; O Baron; J Crack; C Coulber; G J Wilson; M Rabinovitch
Journal:  J Clin Invest       Date:  1996-06-01       Impact factor: 14.808

3.  Increased interleukin-1 beta and fibronectin expression are early features of the development of the postcardiac transplant coronary arteriopathy in piglets.

Authors:  N Clausell; S Molossi; M Rabinovitch
Journal:  Am J Pathol       Date:  1993-06       Impact factor: 4.307

4.  Acute phase protein response and polymorphonuclear leukocyte cathepsin g release after slow interleukin-1 stimulation in the rat.

Authors:  P Björk; T Gudmundsson; K Ohlsson
Journal:  Mediators Inflamm       Date:  1994       Impact factor: 4.711

Review 5.  Biological mechanisms underlying the ultraviolet radiation-induced formation of skin wrinkling and sagging II: over-expression of neprilysin plays an essential role.

Authors:  Genji Imokawa; Hiroaki Nakajima; Koichi Ishida
Journal:  Int J Mol Sci       Date:  2015-04-08       Impact factor: 5.923

Review 6.  Biological mechanisms underlying the ultraviolet radiation-induced formation of skin wrinkling and sagging I: reduced skin elasticity, highly associated with enhanced dermal elastase activity, triggers wrinkling and sagging.

Authors:  Genji Imokawa; Koichi Ishida
Journal:  Int J Mol Sci       Date:  2015-04-08       Impact factor: 5.923

7.  Differential Proliferative Characteristics of Alveolar Fibroblasts in Interstitial Lung Diseases: Regulative Role of IL-1 and PGE(2).

Authors:  E Fireman; S Ben Efraim; J Greif; H Peretz; S Kivity; M Topilsky; Y Rodrig; A Yellin; R N Apte
Journal:  Mediators Inflamm       Date:  1994       Impact factor: 4.711
  7 in total

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