Literature DB >> 20648701

PharmGKB summary: very important pharmacogene information for CYP2B6.

Caroline F Thorn1, Jatinder K Lamba, Vishal Lamba, Teri E Klein, Russ B Altman.   

Abstract

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Year:  2010        PMID： 20648701      PMCID： PMC3086041          DOI： 10.1097/fpc.0b013e32833947c2

Source DB:  PubMed          Journal:  Pharmacogenet Genomics        ISSN： 1744-6872            Impact factor:   2.089


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  37 in total

1.  Extensive genetic polymorphism in the human CYP2B6 gene with impact on expression and function in human liver.

Authors:  T Lang; K Klein; J Fischer; A K Nüssler; P Neuhaus; U Hofmann; M Eichelbaum; M Schwab; U M Zanger
Journal:  Pharmacogenetics       Date:  2001-07

2.  Role of polymorphic human CYP2B6 in cyclophosphamide bioactivation.

Authors:  H-J Xie; U Yasar; S Lundgren; L Griskevicius; Y Terelius; M Hassan; A Rane
Journal:  Pharmacogenomics J       Date:  2003       Impact factor: 3.550

3.  Regulation of the human CYP2B6 gene by the nuclear pregnane X receptor.

Authors:  B Goodwin; L B Moore; C M Stoltz; D D McKee; S A Kliewer
Journal:  Mol Pharmacol       Date:  2001-09       Impact factor: 4.436

4.  Functional characterization of cytochrome P450 2B6 allelic variants.

Authors:  Hideto Jinno; Toshiko Tanaka-Kagawa; Akiko Ohno; Yuko Makino; Erika Matsushima; Nobumitsu Hanioka; Masanori Ando
Journal:  Drug Metab Dispos       Date:  2003-04       Impact factor: 3.922

5.  Bupropion and 4-OH-bupropion pharmacokinetics in relation to genetic polymorphisms in CYP2B6.

Authors:  Julia Kirchheiner; Christian Klein; Ingolf Meineke; Johanna Sasse; Ulrich M Zanger; Thomas E Mürdter; Ivar Roots; Jürgen Brockmöller
Journal:  Pharmacogenetics       Date:  2003-10

6.  Pharmacogenetic determinants of interindividual variability in bupropion hydroxylation by cytochrome P450 2B6 in human liver microsomes.

Authors:  Leah M Hesse; Ping He; Soundararajan Krishnaswamy; Qin Hao; Kirk Hogan; Lisa L von Moltke; David J Greenblatt; Michael H Court
Journal:  Pharmacogenetics       Date:  2004-04

7.  A novel distal enhancer module regulated by pregnane X receptor/constitutive androstane receptor is essential for the maximal induction of CYP2B6 gene expression.

Authors:  Hongbing Wang; Stephanie Faucette; Tatsuya Sueyoshi; Rick Moore; Stephen Ferguson; Masahiko Negishi; Edward L LeCluyse
Journal:  J Biol Chem       Date:  2003-02-05       Impact factor: 5.157

8.  Hepatic CYP2B6 expression: gender and ethnic differences and relationship to CYP2B6 genotype and CAR (constitutive androstane receptor) expression.

Authors:  Vishal Lamba; Jatinder Lamba; Kazuto Yasuda; Stephen Strom; Julio Davila; Michael L Hancock; James D Fackenthal; Peter K Rogan; Barbara Ring; Steven A Wrighton; Erin G Schuetz
Journal:  J Pharmacol Exp Ther       Date:  2003-10-09       Impact factor: 4.030

9.  Homozygous CYP2B6 *6 (Q172H and K262R) correlates with high plasma efavirenz concentrations in HIV-1 patients treated with standard efavirenz-containing regimens.

Authors:  Kiyoto Tsuchiya; Hiroyuki Gatanaga; Natsuo Tachikawa; Katsuji Teruya; Yoshimi Kikuchi; Munehiro Yoshino; Takeshi Kuwahara; Takuma Shirasaka; Satoshi Kimura; Shinichi Oka
Journal:  Biochem Biophys Res Commun       Date:  2004-07-09       Impact factor: 3.575

10.  Smoking, alcoholism and genetic polymorphisms alter CYP2B6 levels in human brain.

Authors:  Sharon Miksys; Caryn Lerman; Peter G Shields; Deborah C Mash; Rachel F Tyndale
Journal:  Neuropharmacology       Date:  2003-07       Impact factor: 5.250
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  29 in total

1.  The P450 oxidoreductase (POR) rs2868177 and cytochrome P450 (CYP) 2B6*6 polymorphisms contribute to the interindividual variability in human CYP2B6 activity.

Authors:  Li-Chen Gao; Fang-Qun Liu; Li Yang; Lin Cheng; Hai-Ying Dai; Ran Tao; Shi-Peng Cao; Di Wang; Jie Tang
Journal:  Eur J Clin Pharmacol       Date:  2016-07-20       Impact factor: 2.953

2.  Impact of Single Nucleotide Polymorphisms on Plasma Concentrations of Efavirenz and Lopinavir/Ritonavir in Chinese Children Infected with the Human Immunodeficiency Virus.

Authors:  Xia Liu; Qing Ma; Yan Zhao; Weiwei Mu; Xin Sun; Yuewu Cheng; Huiping Zhang; Ye Ma; Fujie Zhang
Journal:  Pharmacotherapy       Date:  2017-09-03       Impact factor: 4.705

3.  Pharmacogenetics and pharmacokinetics of CNS penetration of efavirenz and its metabolites.

Authors:  Eric H Decloedt; Phumla Z Sinxadi; Gert U van Zyl; Lubbe Wiesner; Saye Khoo; John A Joska; David W Haas; Gary Maartens
Journal:  J Antimicrob Chemother       Date:  2019-03-01       Impact factor: 5.790

4.  The influence of sex, ethnicity, and CYP2B6 genotype on bupropion metabolism as an index of hepatic CYP2B6 activity in humans.

Authors:  Katarina Ilic; Roy L Hawke; Ranjit K Thirumaran; Erin G Schuetz; J Heyward Hull; Angela D M Kashuba; Paul W Stewart; Celeste M Lindley; Mei-Ling Chen
Journal:  Drug Metab Dispos       Date:  2012-12-13       Impact factor: 3.922

Review 5.  Pharmacogenomics of methadone: a narrative review of the literature.

Authors:  Senthil Packiasabapathy; Blessed W Aruldhas; Nicole Horn; Brian R Overholser; Sara K Quinney; Janelle S Renschler; Senthilkumar Sadhasivam
Journal:  Pharmacogenomics       Date:  2020-07-24       Impact factor: 2.533

Review 6.  Bioinformatics and variability in drug response: a protein structural perspective.

Authors:  Jennifer L Lahti; Grace W Tang; Emidio Capriotti; Tianyun Liu; Russ B Altman
Journal:  J R Soc Interface       Date:  2012-05-02       Impact factor: 4.118

7.  CYP2B6*6 or Not CYP2B6*6-That Remains a Question for Precision Medicine and Ketamine!

Authors:  Scott D Cook-Sather; Peter C Adamson; Jin Li; Hakon Hakonarson
Journal:  Anesthesiology       Date:  2016-12       Impact factor: 7.892

8.  Effect of Gambogenic Acid on Cytochrome P450 1A2, 2B1 and 2E1, and Constitutive Androstane Receptor in Rats.

Authors:  Jing Sun; Xiaozhu Tang; Qianqian Xu; Tao Ge; Daiyin Peng; Weidong Chen
Journal:  Eur J Drug Metab Pharmacokinet       Date:  2018-12       Impact factor: 2.441

9.  A Global Health Diagnostic for Personalized Medicine in Resource-Constrained World Settings: A Simple PCR-RFLP Method for Genotyping CYP2B6 g.15582C>T and Science and Policy Relevance for Optimal Use of Antiretroviral Drug Efavirenz.

Authors:  Jonathan Evans; Marelize Swart; Nyarai Soko; Ambroise Wonkam; Farah Huzair; Collet Dandara
Journal:  OMICS       Date:  2015-06

10.  Variation in CYP2A6 and tobacco dependence throughout adolescence and in young adult smokers.

Authors:  Meghan J Chenoweth; Marie-Pierre Sylvestre; Gisele Contreras; Maria Novalen; Jennifer O'Loughlin; Rachel F Tyndale
Journal:  Drug Alcohol Depend       Date:  2015-11-21       Impact factor: 4.492
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