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Literature DB >> 20648403

Cathepsins and their involvement in immune responses.

Abstract

The immune system is composed of an enormous variety of cells and molecules that generate a collective and coordinated response on exposure to foreign antigens, called the immune response. Within the immune response, endo-lysosomal proteases play a key role. In this review we cover specific roles of cathepsins in innate and adaptive immunity, as well as their implication in the pathogenesis of several diseases.

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Year: 2010 PMID： 20648403 DOI： 10.4414/smw.2010.13042

Source DB: PubMed Journal: Swiss Med Wkly ISSN： 0036-7672 Impact factor: 2.193

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Cited

76 in total

1. Predictions versus high-throughput experiments in T-cell epitope discovery: competition or synergy?

Authors: Claus Lundegaard; Ole Lund; Morten Nielsen
Journal: Expert Rev Vaccines Date: 2012-01 Impact factor: 5.217

2. Cathepsin L in the orange-spotted grouper, Epinephelus coioides: molecular cloning and gene expression after a Vibrio anguillarum challenge.

Authors: Jing-Zhen Liang; Ying-Zhu Rao; Zhao-Rong Lun; Ting-Bao Yang
Journal: Fish Physiol Biochem Date: 2012-06-22 Impact factor: 2.794

3. Odanacatib, A Cathepsin K-Specific Inhibitor, Inhibits Inflammation and Bone Loss Caused by Periodontal Diseases.

Authors: Liang Hao; Jianwei Chen; Zheng Zhu; Michael S Reddy; John D Mountz; Wei Chen; Yi-Ping Li
Journal: J Periodontol Date: 2015-04-16 Impact factor: 6.993

4. Initial symbiont contact orchestrates host-organ-wide transcriptional changes that prime tissue colonization.

Authors: Natacha Kremer; Eva E R Philipp; Marie-Christine Carpentier; Caitlin A Brennan; Lars Kraemer; Melissa A Altura; René Augustin; Robert Häsler; Elizabeth A C Heath-Heckman; Suzanne M Peyer; Julia Schwartzman; Bethany A Rader; Edward G Ruby; Philip Rosenstiel; Margaret J McFall-Ngai
Journal: Cell Host Microbe Date: 2013-08-14 Impact factor: 21.023

10. Dengue virus infection of the Aedes aegypti salivary gland and chemosensory apparatus induces genes that modulate infection and blood-feeding behavior.

Authors: Shuzhen Sim; José L Ramirez; George Dimopoulos
Journal: PLoS Pathog Date: 2012-03-29 Impact factor: 6.823

Cathepsins and their involvement in immune responses.

1. Predictions versus high-throughput experiments in T-cell epitope discovery: competition or synergy?

2. Cathepsin L in the orange-spotted grouper, Epinephelus coioides: molecular cloning and gene expression after a Vibrio anguillarum challenge.

3. Odanacatib, A Cathepsin K-Specific Inhibitor, Inhibits Inflammation and Bone Loss Caused by Periodontal Diseases.

4. Initial symbiont contact orchestrates host-organ-wide transcriptional changes that prime tissue colonization.

5. The Outcome of the Cryptococcus neoformans-Macrophage Interaction Depends on Phagolysosomal Membrane Integrity.

6. Affinity-Enhanced Luminescent Re(I)- and Ru(II)-Based Inhibitors of the Cysteine Protease Cathepsin L.

7. The immunotranscriptome of the Caribbean reef-building coral Pseudodiploria strigosa.

Review 8. Proteolysis mediated by cysteine cathepsins and legumain-recent advances and cell biological challenges.

Review 9. Biological targets and mechanisms of action of natural products from marine cyanobacteria.

10. Dengue virus infection of the Aedes aegypti salivary gland and chemosensory apparatus induces genes that modulate infection and blood-feeding behavior.