Literature DB >> 20646718

Short-term and long-term results of cardiac surgery in elderly and very elderly patients.

Giuseppe Speziale1, Giuseppe Nasso, Maria Cristina Barattoni, Giampiero Esposito, Georges Popoff, Vincenzo Argano, Ernesto Greco, Marcio Scorcin, Claudio Zussa, Donald Cristell, Roberto Coppola, Sergio Chierchia, Alfredo Marchese, Pasquale Caldarola, Khalil Fattouch, Luigi Tavazzi.   

Abstract

OBJECTIVE: Cardiac operations in elderly patients are increasingly frequent and imply major clinical, ethical, and economic issues. Operative and 5-year results of cardiac operations in patients aged 79 years or more are known in limited series, and a debate is ongoing on the appropriateness of selection of patients for surgery.
METHODS: We retrospectively reviewed our experience in 6802 patients aged 79 years or more who had received a cardiac operation. Surgical candidates were selected according to functional status, crude operative risk, and social context and were managed according to a multimodality protocol.
RESULTS: Mean age was 82 years and surgery was nonelective in 1613 cases (23.5%, 31 salvage). Procedures consisted of valve replacement (aortic, 2817; mitral, 532; and tricuspid, 2 cases), valve repair (aortic, 66; mitral, 532; and tricuspid, 232 cases), coronary bypass grafting (12,034 coronary vessels bypassed), and replacement of the thoracic aorta (ascending, 315; arch, 28 cases). Overall operative mortality was 3.4%. Nonelective presentation, need for aortic counterpulsation, cardiopulmonary bypass time, blood transfusion, depressed systolic function, and chronic lung disease predicted operative mortality. Five-year cumulative mortality was 7.5%. Poor systolic function, previous myocardial infarction, and combined coronary/mitral surgery predicted late mortality. The operative risk of nonagenarians operated on electively did not differ from that of risk-matched octogenarians.
CONCLUSIONS: Cardiac surgery in elderly and very elderly patients can be performed with acceptable mortality provided that accurate selection and a multifactorial risk evaluation are adopted. Whenever possible, nonelective operations should be avoided and earlier surgery should be encouraged. Five-year survival and functional recovery are good.
Copyright © 2011 The American Association for Thoracic Surgery. Published by Mosby, Inc. All rights reserved.

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Year:  2010        PMID: 20646718     DOI: 10.1016/j.jtcvs.2010.05.010

Source DB:  PubMed          Journal:  J Thorac Cardiovasc Surg        ISSN: 0022-5223            Impact factor:   5.209


  12 in total

Review 1.  Under-prescribing and non-adherence to medications after coronary bypass surgery in older adults: strategies to improve adherence.

Authors:  David Sengstock; Peter Vaitkevicius; Ahmed Salama; Robert M Mentzer
Journal:  Drugs Aging       Date:  2012-02-01       Impact factor: 3.923

2.  Estimating the adoption of transcatheter aortic valve replacement by US interventional cardiologists and clinical trialists.

Authors:  Joshua M Stolker; Akshar Y Patel; Michael J Lim; Paul J Hauptman
Journal:  Clin Cardiol       Date:  2013-08-27       Impact factor: 2.882

3.  The outcomes of the elderly in acute care general surgery.

Authors:  E St-Louis; M Sudarshan; M Al-Habboubi; M El-Husseini Hassan; D L Deckelbaum; T S Razek; L S Feldman; K Khwaja
Journal:  Eur J Trauma Emerg Surg       Date:  2015-04-08       Impact factor: 3.693

4.  Can a Multifaceted Intervention Including Motivational Interviewing Improve Medication Adherence, Quality of Life, and Mortality Rates in Older Patients Undergoing Coronary Artery Bypass Surgery? A Multicenter, Randomized Controlled Trial with 18-Month Follow-Up.

Authors:  Chung-Ying Lin; Mehdi Yaseri; Amir H Pakpour; Dan Malm; Anders Broström; Bengt Fridlund; Andrea Burri; Thomas L Webb
Journal:  Drugs Aging       Date:  2017-02       Impact factor: 3.923

5.  Association of Integrated Care Coordination With Postsurgical Outcomes in High-Risk Older Adults: The Perioperative Optimization of Senior Health (POSH) Initiative.

Authors:  Shelley R McDonald; Mitchell T Heflin; Heather E Whitson; Thomas O Dalton; Michael E Lidsky; Phillip Liu; Cornelia M Poer; Richard Sloane; Julie K Thacker; Heidi K White; Mamata Yanamadala; Sandhya A Lagoo-Deenadayalan
Journal:  JAMA Surg       Date:  2018-05-01       Impact factor: 14.766

6.  Cardiac surgery in the very elderly: it isn't all about survival.

Authors:  Ishtiaq Ali Rahman; Simon Kendall
Journal:  Br J Cardiol       Date:  2020-03-04

Review 7.  Does Age Affect the Short- and Long-Term Outcomes of Coronary Bypass Grafting?

Authors:  Pavan Ashwini Anand; Suresh Keshavamurthy; Ellis M Shelley; Sibu Saha
Journal:  Int J Angiol       Date:  2021-08-25

Review 8.  Off-pump coronary artery bypass grafting in octogenarians.

Authors:  Shahzad G Raja
Journal:  J Thorac Dis       Date:  2016-11       Impact factor: 2.895

Review 9.  Hyperkalemic cardioplegia for adult and pediatric surgery: end of an era?

Authors:  Geoffrey P Dobson; Giuseppe Faggian; Francesco Onorati; Jakob Vinten-Johansen
Journal:  Front Physiol       Date:  2013-08-28       Impact factor: 4.566

10.  Coronary artery bypass grafting in the octogenarians: should we intervene, or leave them be?

Authors:  Anil Ozen; Ertekin Utku Unal; Murat Songur; Sinan Sabit Kocabeyoglu; Onur Hanedan; Metin Yilmaz; Basak Soran Turkcan; Ferit Cicekcioglu; Sadi Kaplan; Cemal Levent Birincioglu
Journal:  J Geriatr Cardiol       Date:  2015-03       Impact factor: 3.327

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