Literature DB >> 20645844

New sesquiterpene coumarins from the roots of Ferula flabelliloba.

Mehrdad Iranshahi1, Farhad Kalategi, Amirhossein Sahebkar, Alireza Sardashti, Bernd Schneider.   

Abstract

Three new sesquiterpene coumarins, namely, farnesiferone B (1), flabellilobin A (2) and flabellilobin B (3), together with nine known compounds, ligupersin A, 7-epi-gamma-eudesmol, persicasulfide A, conferdione, umbelliprenin, conferone, feselol, lehmferin and farnesiferol B were isolated from the roots of Ferula flabelliloba Rech. f. & Aell. (Apiaceae). The structures of these compounds were elucidated by various 1- and 2-D NMR techniques as well as HREIMS.

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Year:  2010        PMID： 20645844     DOI： 10.3109/13880200903019226

Source DB:  PubMed          Journal:  Pharm Biol        ISSN： 1388-0209            Impact factor:   3.503


  9 in total

1.  Umbelliprenin is Potentially Toxic Against the HT29, CT26, MCF-7, 4T1, A172, and GL26 Cell Lines, Potentially Harmful Against Bone Marrow-Derived Stem Cells, and Non-Toxic Against Peripheral Blood Mononuclear Cells.

Authors:  Mohsen Rashidi; Seyed Ali Ziai; Taraneh Moini Zanjani; Ahad Khalilnezhad; Hamidreza Jamshidi; Davar Amani
Journal:  Iran Red Crescent Med J       Date:  2016-05-14       Impact factor: 0.611

2.  The Evaluation and Comparing of Cytotoxic Effects of Ferula gummosa Gum, Scutellaria lindbergii, Kelussia odoratissima and Artemisia kopetdaghensis Extracts on ACHN Cell Line.

Authors:  Azar Hosseini; Elham Bakhtiari; Abolfazl Khajavi Rad; Samira Shahraki; Seyed Hadi Mousavi; Shahrzad Havakhah; Mohammad Sadegh Amiri
Journal:  Iran J Pharm Res       Date:  2017       Impact factor: 1.696

3.  Phytochemical screening and evaluation of the antimicrobial and antioxidant activities of Ferula caspica M. Bieb. extracts.

Authors:  Cigdem Kahraman; Gulacti Topcu; Erdal Bedir; I Irem Tatli; Melike Ekizoglu; Zeliha S Akdemir
Journal:  Saudi Pharm J       Date:  2019-02-02       Impact factor: 4.330

4.  Novel pH-sensitive and biodegradable micelles for the combined delivery of doxorubicin and conferone to induce apoptosis in MDA-MB-231 breast cancer cell line.

Authors:  Akram Rahmani; Hassan Zavvar Mousavi; Roya Salehi; Ahmad Bagheri
Journal:  RSC Adv       Date:  2020-08-07       Impact factor: 4.036

5.  Cytotoxic activities of phytochemicals from Ferula species.

Authors:  Seied Mojtaba Valiahdi; Mehrdad Iranshahi; Amirhossein Sahebkar
Journal:  Daru       Date:  2013-05-23       Impact factor: 3.117

6.  Umbelliprenin is cytotoxic against QU-DB large cell lung cancer cell line but anti-proliferative against A549 adenocarcinoma cells.

Authors:  Narges Khaghanzadeh; Zahra Mojtahedi; Mohammad Ramezani; Nasrollah Erfani; Abbas Ghaderi
Journal:  Daru       Date:  2012-10-30       Impact factor: 3.117

Review 7.  Review of the traditional uses, phytochemistry, pharmacology and toxicology of giant fennel (Ferula communis L. subsp. communis).

Authors:  Maryam Akaberi; Milad Iranshahy; Mehrdad Iranshahi
Journal:  Iran J Basic Med Sci       Date:  2015-11       Impact factor: 2.699

Review 8.  Recent Advances in the Synthesis of Coumarin Derivatives from Different Starting Materials.

Authors:  Melita Lončarić; Dajana Gašo-Sokač; Stela Jokić; Maja Molnar
Journal:  Biomolecules       Date:  2020-01-16

9.  Co-delivery of doxorubicin and conferone by novel pH-responsive β-cyclodextrin grafted micelles triggers apoptosis of metastatic human breast cancer cells.

Authors:  Akram Rahmani; Fariborz Rahimi; Mehrdad Iranshahi; Houman Kahroba; Amir Zarebkohan; Mehdi Talebi; Roya Salehi; Hassan Zavvar Mousavi
Journal:  Sci Rep       Date:  2021-11-02       Impact factor: 4.379
  9 in total

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