| Literature DB >> 20645822 |
Hamid R Monsef-Esfahani1, Reza Hajiaghaee, Ahmad R Shahverdi, Mohammad R Khorramizadeh, Mohsen Amini.
Abstract
No phytochemical investigation regarding Scrophularia striata Boiss. (Scrophulariaceae) has been performed, although several reports about other Scrophularia species have been published. The inhibitory effects of aerial parts of S. striata on matrix metalloproteinase expression elaborate a new approach to treat variety of malignant and inflammatory disorders. Five known compounds, including cinnamic acid, three flavonoids (quercetine, isorhamnetin-3-O-rutinoside and nepitrin) and one phenyl propanoid glycoside (acteoside 1) were isolated from S. striata Boiss. by chromatographic techniques and the structures of compounds were characterized by spectroscopic methods. This is the first report regarding the isolation of these compounds from S. striata.Entities:
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Year: 2010 PMID: 20645822 DOI: 10.3109/13880200903133829
Source DB: PubMed Journal: Pharm Biol ISSN: 1388-0209 Impact factor: 3.503