BACKGROUND: The purpose of this study was to determine factors to predict the success of free flap surgery in the treatment of osteoradionecrosis (ORN). METHODS: Univariate analysis of overall and flap complications was performed. The effect of time to ORN, and the time interval between ORN to reconstruction was evaluated. RESULTS: Fifty-five flaps on 53 patients for ORN were done with a 90% resolution rate. Univariate parameter analysis was significant for infield mandibulotomy. An increased time interval from radiation therapy (XRT) to ORN development significantly predicted for flap-specific complications and flap loss (p < .05). Increased time from ORN diagnosis to flap surgery resulted in greater length of bone involvement (p = .01). Anastomotic complications occurred in 13 cases resulting in 7 complete flap losses. CONCLUSION: An increased risk of complication was encountered with greater time from XRT to ORN. Thus, in patients developing ORN long after treatment, surgery should be accordingly more aggressive.
BACKGROUND: The purpose of this study was to determine factors to predict the success of free flap surgery in the treatment of osteoradionecrosis (ORN). METHODS: Univariate analysis of overall and flap complications was performed. The effect of time to ORN, and the time interval between ORN to reconstruction was evaluated. RESULTS: Fifty-five flaps on 53 patients for ORN were done with a 90% resolution rate. Univariate parameter analysis was significant for infield mandibulotomy. An increased time interval from radiation therapy (XRT) to ORN development significantly predicted for flap-specific complications and flap loss (p < .05). Increased time from ORN diagnosis to flap surgery resulted in greater length of bone involvement (p = .01). Anastomotic complications occurred in 13 cases resulting in 7 complete flap losses. CONCLUSION: An increased risk of complication was encountered with greater time from XRT to ORN. Thus, in patients developing ORN long after treatment, surgery should be accordingly more aggressive.
Authors: John T Nguyen; Yoshitomo Ashitate; Ian A Buchanan; Ahmed M S Ibrahim; Sylvain Gioux; Priti P Patel; John V Frangioni; Bernard T Lee Journal: J Surg Res Date: 2012-05-24 Impact factor: 2.192
Authors: Larissa Sweeny; William P Lancaster; Nichole R Dean; J Scott Magnuson; William R Carroll; Patrick J Louis; Eben L Rosenthal Journal: J Oral Maxillofac Surg Date: 2011-12-16 Impact factor: 1.895
Authors: Kevin J Contrera; Steven B Chinn; Randal S Weber; Dianna Roberts; Jeffery N Myers; Stephen Y Lai; Carol M Lewis; Amy C Hessel; Ann M Gillenwater; Collin F Mulcahy; Peirong Yu; Matthew M Hanasono; Clifton D Fuller; Mark S Chambers; Mark E Zafereo Journal: Head Neck Date: 2022-03-03 Impact factor: 3.821
Authors: Kongkrit Chaiyasate; Rohun Gupta; Jithin John; Sean Chaiyasate; Jeremy Powers; Alan Nguyen; Christopher Issa; Justin Hart; Joshua J Goldman; Neil S Sachanandani Journal: Plast Reconstr Surg Glob Open Date: 2022-08-24