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Literature DB >> 20644581

Life-threatening reversible acidosis caused by alcohol abuse.

Abstract

BACKGROUND: A 52-year-old man with a history of alcohol dependency was admitted to the emergency room with life-threatening anion gap metabolic acidosis. He admitted to drinking large quantities of alcohol during the previous day. INVESTIGATIONS: Physical examination, blood and urine analyses, including calculation of his anion gap and plasma osmolal gap, and measurement of serum alcohol levels. DIAGNOSIS: Severe but rapidly reversible lactic acidosis and associated alcohol-induced ketoacidosis. MANAGEMENT: Intravenous thiamine, intravenous fluids and bicarbonate.

Entities: Chemical Disease Species

Mesh：

Year: 2010 PMID： 20644581 DOI： 10.1038/nrneph.2010.99

Source DB: PubMed Journal: Nat Rev Nephrol ISSN： 1759-5061 Impact factor: 28.314

30 in total

Review 1. Survival from profound alcohol-related lactic acidosis.

Authors: D Lien; T J Mader
Journal: J Emerg Med Date: 1999 Sep-Oct Impact factor: 1.484

2. Lactic acidosis traced to thiamine deficiency related to nationwide shortage of multivitamins for total parenteral nutrition -- United States, 1997.

Authors:
Journal: MMWR Morb Mortal Wkly Rep Date: 1997-06-13 Impact factor: 17.586

Life-threatening reversible acidosis caused by alcohol abuse.

Review 1. Survival from profound alcohol-related lactic acidosis.

2. Lactic acidosis traced to thiamine deficiency related to nationwide shortage of multivitamins for total parenteral nutrition -- United States, 1997.

3. Clinical studies of alcoholic ketoacidosis.

4. Increased osmolal gap in alcoholic ketoacidosis and lactic acidosis.

5. Fomepizole for the treatment of ethylene glycol poisoning. Methylpyrazole for Toxic Alcohols Study Group.

6. Metabolic acidosis in the alcoholic: a pathophysiologic approach.

7. Severe lactic acidosis and thiamine deficiency during total parenteral nutrition--case report.

Review 8. Acidosis in a patient with cholera: a need to redefine concepts.

Review 9. Serum anion gap: its uses and limitations in clinical medicine.

10. Treatment of alcoholic acidosis: the role of dextrose and phosphorus.

1. Obscure Severe Infrarenal Aortoiliac Stenosis With Severe Transient Lactic Acidosis.

2. Prognosis of alcohol-associated lactic acidosis in critically ill patients: an 8-year study.