Literature DB >> 20643685

The Virtual Physiological Human ToolKit.

Jonathan Cooper1, Frederic Cervenansky, Gianni De Fabritiis, John Fenner, Denis Friboulet, Toni Giorgino, Steven Manos, Yves Martelli, Jordi Villà-Freixa, Stefan Zasada, Sharon Lloyd, Keith McCormack, Peter V Coveney.   

Abstract

The Virtual Physiological Human (VPH) is a major European e-Science initiative intended to support the development of patient-specific computer models and their application in personalized and predictive healthcare. The VPH Network of Excellence (VPH-NoE) project is tasked with facilitating interaction between the various VPH projects and addressing issues of common concern. A key deliverable is the 'VPH ToolKit'--a collection of tools, methodologies and services to support and enable VPH research, integrating and extending existing work across Europe towards greater interoperability and sustainability. Owing to the diverse nature of the field, a single monolithic 'toolkit' is incapable of addressing the needs of the VPH. Rather, the VPH ToolKit should be considered more as a 'toolbox' of relevant technologies, interacting around a common set of standards. The latter apply to the information used by tools, including any data and the VPH models themselves, and also to the naming and categorizing of entities and concepts involved. Furthermore, the technologies and methodologies available need to be widely disseminated, and relevant tools and services easily found by researchers. The VPH-NoE has thus created an online resource for the VPH community to meet this need. It consists of a database of tools, methods and services for VPH research, with a Web front-end. This has facilities for searching the database, for adding or updating entries, and for providing user feedback on entries. Anyone is welcome to contribute.

Entities:  

Mesh:

Year:  2010        PMID: 20643685     DOI: 10.1098/rsta.2010.0144

Source DB:  PubMed          Journal:  Philos Trans A Math Phys Eng Sci        ISSN: 1364-503X            Impact factor:   4.226


  5 in total

1.  A tool for multi-scale modelling of the renal nephron.

Authors:  David P Nickerson; Jonna R Terkildsen; Kirk L Hamilton; Peter J Hunter
Journal:  Interface Focus       Date:  2011-03-30       Impact factor: 3.906

2.  Audited credential delegation: a usable security solution for the virtual physiological human toolkit.

Authors:  Ali N Haidar; Stefan J Zasada; Peter V Coveney; Ali E Abdallah; Bruce Beckles; Mike A S Jones
Journal:  Interface Focus       Date:  2011-03-30       Impact factor: 3.906

3.  Module-based multiscale simulation of angiogenesis in skeletal muscle.

Authors:  Gang Liu; Amina A Qutub; Prakash Vempati; Feilim Mac Gabhann; Aleksander S Popel
Journal:  Theor Biol Med Model       Date:  2011-04-04       Impact factor: 2.432

4.  STI-GMaS: an open-source environment for simulation of sexually-transmitted infections.

Authors:  Martin R Nelson; Kelly J Sutton; Bindi S Brook; Dann G Mallet; Daniel P Simpson; Roger G Rank
Journal:  BMC Syst Biol       Date:  2014-06-12

5.  Chaste: an open source C++ library for computational physiology and biology.

Authors:  Gary R Mirams; Christopher J Arthurs; Miguel O Bernabeu; Rafel Bordas; Jonathan Cooper; Alberto Corrias; Yohan Davit; Sara-Jane Dunn; Alexander G Fletcher; Daniel G Harvey; Megan E Marsh; James M Osborne; Pras Pathmanathan; Joe Pitt-Francis; James Southern; Nejib Zemzemi; David J Gavaghan
Journal:  PLoS Comput Biol       Date:  2013-03-14       Impact factor: 4.475

  5 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.