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Literature DB >> 20643311

Imaging-genetics applications in child psychiatry.

Daniel S Pine¹, Monique Ernst, Ellen Leibenluft.

Abstract

OBJECTIVE: To place imaging-genetics research in the context of child psychiatry.
METHOD: A conceptual overview is provided, followed by discussion of specific research examples.
RESULTS: Imaging-genetics research is described linking brain function to two specific genes, for the serotonin-reuptake-transporter protein and a monoamine oxidase enzyme. Work is then described on phenotype selection in imaging genetics.
CONCLUSIONS: Child psychiatry applications of imaging genetics are only beginning to emerge. The approach holds promise for advancing understandings of pathophysiology and therapeutics. 2010 American Academy of Child and Adolescent Psychiatry. Published by Elsevier Inc. All rights reserved.

Entities: Chemical Disease Gene Mutation Species

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Year: 2010 PMID： 20643311 PMCID： PMC2997350 DOI： 10.1016/j.jaac.2009.12.022

Source DB: PubMed Journal: J Am Acad Child Adolesc Psychiatry ISSN： 0890-8567 Impact factor: 8.829

55 in total

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3. Bias in genetic association studies and impact factor.

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5. Neural correlates of genetically abnormal social cognition in Williams syndrome.

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6. Incorporating language phenotypes strengthens evidence of linkage to autism.

Authors: Y Bradford; J Haines; H Hutcheson; M Gardiner; T Braun; V Sheffield; T Cassavant; W Huang; K Wang; V Vieland; S Folstein; S Santangelo; J Piven
Journal: Am J Med Genet Date: 2001-08-08

Review 7. Neurophysiological endophenotypes of schizophrenia: the viability of selected candidate measures.

Authors: Bruce I Turetsky; Monica E Calkins; Gregory A Light; Ann Olincy; Allen D Radant; Neal R Swerdlow
Journal: Schizophr Bull Date: 2006-11-29 Impact factor: 9.306

8. Dopamine transporter genotype conveys familial risk of attention-deficit/hyperactivity disorder through striatal activation.

Authors: Sarah Durston; John A Fossella; Martijn J Mulder; B J Casey; Tim B Ziermans; M Nathalie Vessaz; Herman VAN Engeland
Journal: J Am Acad Child Adolesc Psychiatry Date: 2008-01 Impact factor: 8.829

Review 9. Can neuroscience be integrated into the DSM-V?

Authors: Steven E Hyman
Journal: Nat Rev Neurosci Date: 2007-09 Impact factor: 34.870

Review 10. Challenges in developing novel treatments for childhood disorders: lessons from research on anxiety.

Authors: Daniel S Pine; Sarah M Helfinstein; Yair Bar-Haim; Eric Nelson; Nathan A Fox
Journal: Neuropsychopharmacology Date: 2008-08-27 Impact factor: 7.853

5 in total

Review 1. Neuroimaging of the Philadelphia neurodevelopmental cohort.

Authors: Theodore D Satterthwaite; Mark A Elliott; Kosha Ruparel; James Loughead; Karthik Prabhakaran; Monica E Calkins; Ryan Hopson; Chad Jackson; Jack Keefe; Marisa Riley; Frank D Mentch; Patrick Sleiman; Ragini Verma; Christos Davatzikos; Hakon Hakonarson; Ruben C Gur; Raquel E Gur
Journal: Neuroimage Date: 2013-08-03 Impact factor: 6.556