Literature DB >> 20640924

[Diuretics-related complications in elderly patients].

Ronald Otto1, Regina E Roller1, Bernhard Iglseder2, Peter Dovjak3, Monika Lechleitner4, Ulrike Sommeregger5, Ursula Benvenuti-Falger4, Birgit Böhmdorfer6, Markus Gosch7.   

Abstract

Diuretics are well studied and evaluated for their beneficial use in geriatric patients. However those drugs are often used without taking care of subjects condition or functional impairment. Known side effects of those substances may be increased by combinations of multiple drugs. Polypharmacy is a strong risk factor for the incidence of adverse drug reactions (ADR). ADRs are frequently found in combination with the use of diuretics. The remodelling of human body in aging process and uncontrolled therapeutic strategies seem to be causal for that finding. This article tries to work out the potential risk of the usage of those drugs in geriatric patients and its clinical relevance by using literature published in PubMed.

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Year:  2010        PMID: 20640924     DOI: 10.1007/s10354-010-0786-1

Source DB:  PubMed          Journal:  Wien Med Wochenschr        ISSN: 0043-5341


  31 in total

1.  Spironolactone-induced gynecomastia.

Authors:  Florim Cuculi; Alex Suter; Paul Erne
Journal:  CMAJ       Date:  2007-02-27       Impact factor: 8.262

Review 2.  Hypernatremic dehydration in the elderly on admission to hospital.

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Journal:  J Nutr Health Aging       Date:  1997       Impact factor: 4.075

Review 3.  Pathophysiology, causes, and prognosis of acute renal failure in the elderly.

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Journal:  Ren Fail       Date:  1996-05       Impact factor: 2.606

Review 4.  [Hypokalemia: diagnosis and treatment].

Authors:  I Katerinis; Z Fumeaux
Journal:  Rev Med Suisse       Date:  2007-03-07

Review 5.  Acute renal failure in the aged.

Authors:  J F Macías-Núñez; J M López-Novoa; M Martínez-Maldonado
Journal:  Semin Nephrol       Date:  1996-07       Impact factor: 5.299

6.  [Potential side-effects and interactions in multiple medication in elderly patients: methodology and results of the Berlin Study of Aging].

Authors:  M Borchelt
Journal:  Z Gerontol Geriatr       Date:  1995 Nov-Dec       Impact factor: 1.281

7.  Severe hyponatremia associated with the combined use of thiazide diuretics and selective serotonin reuptake inhibitors.

Authors:  Mitchell H Rosner
Journal:  Am J Med Sci       Date:  2004-02       Impact factor: 2.378

8.  Severe diuretic-induced hyponatremia in the elderly. A series of eight patients.

Authors:  O S Ashouri
Journal:  Arch Intern Med       Date:  1986-07

9.  Sodium and potassium disturbances in the elderly : prevalence and association with drug use.

Authors:  Galina Passare; Matti Viitanen; Ove Törring; Bengt Winblad; Johan Fastbom
Journal:  Clin Drug Investig       Date:  2004       Impact factor: 2.859

10.  Adverse drug reactions in hospital in-patients: a prospective analysis of 3695 patient-episodes.

Authors:  Emma C Davies; Christopher F Green; Stephen Taylor; Paula R Williamson; David R Mottram; Munir Pirmohamed
Journal:  PLoS One       Date:  2009-02-11       Impact factor: 3.240

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