| Literature DB >> 20639880 |
Xiangdong Liu1, Pietro Invernizzi, Yue Lu, Roman Kosoy, Yan Lu, Ilaria Bianchi, Mauro Podda, Chun Xu, Gang Xie, Fabio Macciardi, Carlo Selmi, Sara Lupoli, Russell Shigeta, Michael Ransom, Ana Lleo, Annette T Lee, Andrew L Mason, Robert P Myers, Kevork M Peltekian, Cameron N Ghent, Francesca Bernuzzi, Massimo Zuin, Floriano Rosina, Elisabetta Borghesio, Annarosa Floreani, Roberta Lazzari, Grazia Niro, Angelo Andriulli, Luigi Muratori, Paolo Muratori, Piero L Almasio, Pietro Andreone, Marzia Margotti, Maurizia Brunetto, Barbara Coco, Domenico Alvaro, Maria C Bragazzi, Fabio Marra, Alessandro Pisano, Cristina Rigamonti, Massimo Colombo, Marco Marzioni, Antonio Benedetti, Luca Fabris, Mario Strazzabosco, Piero Portincasa, Vincenzo O Palmieri, Claudio Tiribelli, Lory Croce, Savino Bruno, Sonia Rossi, Maria Vinci, Cleofe Prisco, Alberto Mattalia, Pierluigi Toniutto, Antonio Picciotto, Andrea Galli, Carlo Ferrari, Silvia Colombo, Giovanni Casella, Lorenzo Morini, Nicola Caporaso, Agostino Colli, Giancarlo Spinzi, Renzo Montanari, Peter K Gregersen, E Jenny Heathcote, Gideon M Hirschfield, Katherine A Siminovitch, Christopher I Amos, M Eric Gershwin, Michael F Seldin.
Abstract
A genome-wide association screen for primary biliary cirrhosis risk alleles was performed in an Italian cohort. The results from the Italian cohort replicated IL12A and IL12RB associations, and a combined meta-analysis using a Canadian dataset identified newly associated loci at SPIB (P = 7.9 x 10(-11), odds ratio (OR) = 1.46), IRF5-TNPO3 (P = 2.8 x 10(-10), OR = 1.63) and 17q12-21 (P = 1.7 x 10(-10), OR = 1.38).Entities:
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Year: 2010 PMID： 20639880 PMCID： PMC3150510 DOI： 10.1038/ng.627
Source DB: PubMed Journal: Nat Genet ISSN： 1061-4036 Impact factor: 38.330